Browse our Research Articles

Page 31 of 1,434
    1. Genetics and Genomics

    A genome-wide association study implicates the olfactory system in Drosophila melanogaster diapause-associated lifespan extension and fecundity

    Sreesankar Easwaran, Denise J Montell
    A genome-wide association study identifies 291 candidate genes for diapause and implicates olfactory pathway genes and cells in the regulation of this adaptive dormancy program in Drosophila.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Balancing reaction-diffusion network for cell polarization pattern with stability and asymmetry

    Yixuan Chen, Guoye Guan ... Chao Tang
    Reaction-diffusion network modeling unveils general design principles that both stabilize cell polarization patterns and enable tunable interface localization, reconciling extensive experimental observations and deepening the understanding of asymmetric cell division.
    1. Immunology and Inflammation
    2. Neuroscience

    Photoreceptor loss does not recruit neutrophils despite strong microglial activation

    Derek Power, Justin Elstrott, Jesse Schallek
    Systemic neutrophils do not respond to laser-induced photoreceptor damage despite the robust response from resident microglia.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Cellular coordination underpins rapid reversals in gliding filamentous cyanobacteria and its loss results in plectonemes

    Jerko Rosko, Rebecca N Poon ... Orkun S Soyer
    Gliding multicellular cyanobacteria results from cellular coordination, the loss of which results in the collapse of orderly back-and-forth movement of filaments and in filament buckling.
    1. Neuroscience

    Increased listening effort and cochlear neural degeneration underlie speech-in-noise deficits in normal-hearing middle-aged adults

    Maggie E Zink, Leslie Zhen ... Aravindakshan Parthasarathy
    Cochlear neural degeneration in middle-aged adults with normal-hearing thresholds is associated with increased listening effort and behavioral deficits in challenging acoustic environments.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Modular DNA barcoding of nanobodies enables multiplexed in situ protein imaging and high-throughput biomolecule detection

    Shilin Zhong, Ruiyu Wang ... Minmin Luo
    A modular DNA barcoding strategy enables efficient multiplexed protein detection for both in situ imaging and high-throughput molecular diagnostics.
    1. Evolutionary Biology

    An initial report of circa 241,000- to 335,000-year-old rock engravings and their relation to Homo naledi in the Rising Star cave system, South Africa

    Lee R Berger, John Hawks ... Keneiloe Molopyane
    Engraved features found within the Dinaledi Subsystem are interpreted as being made by Homo naledi in the absence of evidence of other candidate makers.
    1. Neuroscience

    Neural circuit mechanisms for steering control in walking Drosophila

    Aleksandr Rayshubskiy, Stephen L Holtz ... Rachel Wilson
    Two descending neurons with distinct dynamics contribute to steering, including one influenced by both memory-guided and sensory-driven signals.
    1. Neuroscience

    Methamphetamine-induced adaptation of learning rate dynamics depend on baseline performance

    Hans Kirschner, Hanna M Molla ... Markus Ullsperger
    In individuals with moderately low baseline performance, methamphetamine reduces the tendency to misinterpret high outcome noise.
    1. Neuroscience

    Cntnap2 loss drives striatal neuron hyperexcitability and behavioral inflexibility

    Katherine R Cording, Emilie M Tu ... Helen S Bateup
    Deletion of the neurodevelopmental disorder gene Cntnap2 increases repetitive behaviors in mice and enhances the excitability of striatal direct pathway neurons through decreased potassium channel function.