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Brain-derived neurotrophic factor/tropomyosin receptor kinase B signaling in promoting the differentiation and dentin-repair capacity of dental stem cells under inflammatory conditions offers a potential clinical strategy for repairing damaged teeth.

Leucokinin neurons integrate sweet and bitter taste inputs with starvation signals to regulate feeding initiation, balancing nutrient intake against the risk of toxin ingestion.

Quantitative measurements of intra-Golgi transport kinetics of diverse secretory cargos challenge the classic cisternal progression model and support the stable compartment model of the Golgi.

The evolution of hunting behavior in fish larvae has arrived at different, species-specific solutions, recombining a shared repertoire of locomotor and eye movement motifs.

CRP/cAMP plays a crucial role in the metabolic shift of Escherichia coli persisters from an anabolic state to oxidative phosphorylation, which is essential for their survival during antibiotic treatment.

β-Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.

CryoEM, genetic, and cell biological analyses reveal that the conserved membrane protein CisA mediates membrane recruitment of contractile injection systems Streptomyces coelicolor, enabling their activation under stress.

Polyunsaturated fatty acids are not genetically replaceable in the nematode C. elegans and only mutations that help free ferrous ions can boost the activity of a poorly functioning desaturase enzyme.

Magnetically steered mesenchymal stem cells significantly lowered intraocular pressure for 9 months in mice, motivating the translation of this technology for the treatment of glaucoma.

CHMP5 is crucial in preventing skeletal progenitor cell senescence and abnormal bone formation, and senolytic drugs represent potential therapeutic medicine for musculoskeletal abnormalities associated with a dysfunctional endolysosomal pathway.