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When two signals increase transcription of the same gene, their combined effect tends to reflect either the sum of the individual increases or the product of the individual fold-changes.

Simultaneous voltage and calcium two-photon imaging of Purkinje neuron dendrites in awake mice reveals multiple interplaying mechanisms underlying sensory-evoked dendritic coincidence detection of parallel fiber and climbing fiber input.

Dopamine signals in the ventral, dorsomedial, and dorsolateral striatum are modulated by various variables, such as stimulus-associated value, choice, confidence, but these modulations can be inclusively explained by TD errors.

Intrinsic dynamics are shaped by the intersection of molecular, microstructural, connectomic, and activation gradients.

The shoot meristem becomes domed in shape during floral transition and this is controlled by flowering pathways and the phytohormone gibberellin causing increases in cell size and number.

Def6 functions as a novel immunoregulator in bone cells via endogenous type-I interferon response to regulate bone remodeling.

Admixture dynamics have recently changed over time in Mexican Americans resulting in an impact on the genetic architecture of phenotypic variation.

Diverse muscle spindle firing, critical for a range of sensorimotor behaviors, is compactly explained by first principles of force development in specialized muscle fibers within the sensors.

Disruption of the disease-associated synaptic adhesion molecule Neurexin1a in cortical excitatory neurons perturbs decision making and disrupts value-associated neural activity in downstream striatal circuits.

Adhesion force measurements reveal that proper N-glycosylation of flagellar membrane proteins is crucial for adhering C. reinhardtii cells onto surfaces.