Identification of two molecularly distinct retroperitoneal liposarcoma subtypes, stratifiable via LEP and PTTG1 biomarkers, enables prognosis prediction and informs precision surgical strategies to improve clinical outcomes.
Sara A Nolin, Mary E Faulkner ... Kristina M Visscher
Greater differentiation of brain networks is a hallmark of good cognitive functioning among individuals who have avoided neurodegenerative disease and live longer than a typical human lifespan.
Catherine Suzanne Forconi, Christina Nixon ... Ann M Moormann
Pf-GARP antigen seems to be a better malaria vaccine candidate compared to PfSEA-1A, as it triggered the activation of cTFH17, involved in the maintenance of memory antibody responses in adults.
Monkeys are sensitive to foods coated with tooth-damaging sand and will invest time and energy to eliminate sand, but dominance rank affects the effort allocated to cleaning behaviors.
A femur transplantation model of bone marrow regeneration highlights the plasticity of periosteal skeletal stem cells and their ability to contribute to bone marrow niche regeneration, ultimately facilitating hematopoietic regeneration.
Subcortical brain structures contain neurons encoding subjective reports of stimulus detection in human participants, suggesting a role for conscious perception.
For the first time, mouse models reveal the metabolic dependency of photoreceptors on glutamine catabolism in vivo and further demonstrate the flexibility of photoreceptors to utilize fuel sources beyond glucose.
Co-culture between donor-derived iPSC-induced macrophages and forebrain organoids revealed microglial impairment leading to the degenerative neuro-environment in HDLS.
