Marius Seidenthal, Jasmina Redzovic ... Alexander Gottschalk
Caenorhabditis elegans FLWR-1/Flower is required for efficient synaptic vesicle recycling and does so through a functional and possibly direct physical interaction with the plasma membrane Ca2+ ATPase, MCA-3.
Yasuhiro Arimura, Hide A Konishi, Hironori Funabiki
A technique that enables single-particle cryo-EM analysis of targets on a magnetic bead and a particle curation method that helps structural classification of small particles has been developed.
The SUN1-ALLAN complex serves as a nuclear envelope–spanning tether that coordinates the segregation of a bipartite microtubule organising center (MTOC) during the unusual mitosis of Plasmodium.
A computational study reveals that the kinetic models of Escherichia coli metabolism show strong responsiveness to perturbations and that it originates from cofactor dynamics and network sparsity.
Jordina Rincon-Torroella, Marco Dal Molin ... Surojit Sur
Monocarboxylate transporter 1 overexpressed pancreatic cancers can be therapeutically targeted with ME3BP-7, a promising new agent with unique mode of action.
As a group, inattentionally blind participants can successfully report the location, color, and shape of stimuli they deny noticing, and exhibit a systematic bias to report not noticing.
The determination of GAGases structure facilitates the elucidation of the catalytic mechanism of PL35 family lyases and provides potential evidence for the hypothesis that GAG lyase evolved from alginate lyase.
Solution biophysics defines the influence of local dynamics and allosteric regulation on guide RNA binding affinity and DNA cleavage specificity in a thermophilic Cas9 from Geobacillus stearothermophilus.
It is proposed that place cells are arranged in a hexagonal grid for large surfaces devoid of landmarks, which produces grid cell receptive fields as an artifact of memory retrieval.
