Browse our Research Articles

Page 765 of 1,394
    1. Developmental Biology

    Nodal and planar cell polarity signaling cooperate to regulate zebrafish convergence and extension gastrulation movements

    Margot LK Williams, Lilianna Solnica-Krezel
    Nodal signaling regulates gastrulation cell behaviors largely in parallel with planar cell polarity signaling and is sufficient for ex vivo extension of embryonic explants.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Chromatin accessibility dynamics and single cell RNA-Seq reveal new regulators of regeneration in neural progenitors

    Anneke Dixie Kakebeen, Alexander Daniel Chitsazan ... Andrea Elizabeth Wills
    Regenerating neural progenitors of the Xenopus tropicalis tail prioritize differentiation to motor neuron types earlier than proliferation, a decision partly regulated by the transcription factors Pbx3 and Meis1.
    1. Microbiology and Infectious Disease

    HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread

    Tongcui Ma, Xiaoyu Luo ... Nadia R Roan
    CD4+ T cells from the female reproductive tract are unusually susceptible to HIV infection and are altered by HIV in ways that promote survival and systemic spread of the virus.
    1. Developmental Biology

    Sox8 and Sox9 act redundantly for ovarian-to-testicular fate reprogramming in the absence of R-spondin1 in mouse sex reversals

    Nainoa Richardson, Isabelle Gillot ... Marie-Christine Chaboissier
    Sox8 can induce female-to-male sex reversal of the R-spondin1 loss-of-function mouse mutants in the absence of Sox9..
    1. Cell Biology

    Limitation of adipose tissue by the number of embryonic progenitor cells

    Kristina Hedbacker, Yi-Hsueh Lu ... Jeffrey M Friedman
    The size of subcutaneous, but not visceral, fat depots is dependent on the number of embryonic adipocyte progenitors.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    A molecular filter for the cnidarian stinging response

    Keiko Weir, Christophe Dupre ... Nicholas W Bellono
    Cnidarian stinging cells use a specialized voltage-gated calcium channel to integrate distinct sensory signals and selectively trigger a predatory response.
    1. Cell Biology

    A viral fusogen hijacks the actin cytoskeleton to drive cell-cell fusion

    Ka Man Carmen Chan, Sungmin Son ... Daniel A Fletcher
    A viral fusogen drives cell-cell fusion by hijacking the actin machinery to directly couple actin assembly with a short fusogenic ectodomain.
    1. Neuroscience

    Auditory cortical alpha/beta desynchronization prioritizes the representation of memory items during a retention period

    Nathan Weisz, Nadine Gabriele Kraft, Gianpaolo Demarchi
    Top-down mediated decreases of beta activity in auditory cortex prior to a predictable distractor in an auditory working memory task is associated with increased representation of to-be-memorized information.
    1. Structural Biology and Molecular Biophysics

    Cryo-EM structures and functional properties of CALHM channels of the human placenta

    Katarzyna Drożdżyk, Marta Sawicka ... Raimund Dutzler
    Members of the calcium homeostasis modulator family expressed in the placenta form large channels with unknown activation properties that harbor a lipid bilayer on the inside of a cylindrical pore.
    1. Cell Biology

    Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion

    Julia Damiano-Guercio, Laëtitia Kurzawa ... Jan Faix
    Ena/VASP proteins act as positive regulators of cell motility and are required for the formation of microspikes, as opposed to filopodia that can arise from distinct molecular mechanisms.