Browse our Research Articles

Page 764 of 1,394
    1. Stem Cells and Regenerative Medicine

    Tgfb3 collaborates with PP2A and notch signaling pathways to inhibit retina regeneration

    Mi-Sun Lee, Jin Wan, Daniel Goldman
    Tgfb3 inhibits Muller glial cell reprogramming and drives Muller cell quiescence in the injured zebrafish retina, thereby inhibiting retina regeneration.
    1. Neuroscience

    Spontaneous and evoked neurotransmission are partially segregated at inhibitory synapses

    Patricia M Horvath, Michelle K Piazza ... Ege T Kavalali
    GABAergic postsynaptic responses mediated by spontaneous and evoked neurotransmitter release are partially segregated, suggesting they may serve distinct roles in neuronal signaling.
    1. Developmental Biology

    Yap-lin28a axis targets let7-Wnt pathway to restore progenitors for initiating regeneration

    Zhian Ye, Zhongwu Su ... Linjia Jiang
    Atoh1+ HC precursors survive post severe injury and activate the Yap-Lin28 pathway to restore progenitor for initiating regeneration.
    1. Developmental Biology
    2. Immunology and Inflammation

    Linker histone H1.2 and H1.4 affect the neutrophil lineage determination

    Gabriel Sollberger, Robert Streeck ... Arturo Zychlinsky
    Linker histones affect the lineage determination of granulocyte precursor cells via regulation of the transcription factor GATA-2.
    1. Developmental Biology

    Nodal and planar cell polarity signaling cooperate to regulate zebrafish convergence and extension gastrulation movements

    Margot LK Williams, Lilianna Solnica-Krezel
    Nodal signaling regulates gastrulation cell behaviors largely in parallel with planar cell polarity signaling and is sufficient for ex vivo extension of embryonic explants.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Chromatin accessibility dynamics and single cell RNA-Seq reveal new regulators of regeneration in neural progenitors

    Anneke Dixie Kakebeen, Alexander Daniel Chitsazan ... Andrea Elizabeth Wills
    Regenerating neural progenitors of the Xenopus tropicalis tail prioritize differentiation to motor neuron types earlier than proliferation, a decision partly regulated by the transcription factors Pbx3 and Meis1.
    1. Microbiology and Infectious Disease

    HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread

    Tongcui Ma, Xiaoyu Luo ... Nadia R Roan
    CD4+ T cells from the female reproductive tract are unusually susceptible to HIV infection and are altered by HIV in ways that promote survival and systemic spread of the virus.
    1. Developmental Biology

    Sox8 and Sox9 act redundantly for ovarian-to-testicular fate reprogramming in the absence of R-spondin1 in mouse sex reversals

    Nainoa Richardson, Isabelle Gillot ... Marie-Christine Chaboissier
    Sox8 can induce female-to-male sex reversal of the R-spondin1 loss-of-function mouse mutants in the absence of Sox9..
    1. Cell Biology

    Limitation of adipose tissue by the number of embryonic progenitor cells

    Kristina Hedbacker, Yi-Hsueh Lu ... Jeffrey M Friedman
    The size of subcutaneous, but not visceral, fat depots is dependent on the number of embryonic adipocyte progenitors.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    A molecular filter for the cnidarian stinging response

    Keiko Weir, Christophe Dupre ... Nicholas W Bellono
    Cnidarian stinging cells use a specialized voltage-gated calcium channel to integrate distinct sensory signals and selectively trigger a predatory response.