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High-speed atomic force microscopy reveals that the open state of the divalent ion channel CorA is highly dynamic and defined by the fast exchange between conformations.

Despite differing by only one amino acid in the C-terminal tail, copy 1 of yeast histone 2A has a repair-specific role not shared by copy 2.

The joint combination of interbranch distance and local caliber is sufficient to predict with high accuracy the distribution of myelin internodes along individual axons of neocortical GABAergic interneurons.

Tight nuclear tethering of the cGAS DNA sensor maintains it in its resting state and prevents activation by self-DNA.

GFAP protein carries a distinct post-translational modification signature that facilitates its pathogenic accumulation and aggregation in astrocytes of patients who succumb to Alexander Disease very early in life.

Hawaiian Caenorhabditis elegans harbor high levels of genetic diversity that might represent the complex patterns of ancestral diversity in the species prior to human influence.

Binding of two macromolecular complexes allows kinetochores to capture force produced by the depolymerising ends of microtubules, allowing chromosomes to be transmitted from a mother cell to its two daughters.

Hippocampal axon branching, required for the formation of functional neuronal networks, is regulated by VEGF/VEGFR2 signaling during development.

The internalization of the angiogenic receptor VEGFR2 expressed in neurons is controlled by ephrinB2 and is required for neuronal dendritic arborization, spine morphogenesis and circuitry development in the hippocampus.

The pseudoenzyme CPT1C is able to sense changes in intracellular malonyl-CoA levels caused by nutrients or energy stress and regulate late endosomes/lysosomes anterograde transport, necessary for proper axon growth.