Browse our Research Articles

Page 886 of 1,394
    1. Neuroscience

    Monkey EEG links neuronal color and motion information across species and scales

    Florian Sandhaeger, Constantin von Nicolai ... Markus Siegel
    Using Monkey EEG as a bridge technology, color and motion representations in human MEG are linked to microcircuit activity in ventral stream areas.
    1. Microbiology and Infectious Disease

    A dedicated diribonuclease resolves a key bottleneck for the terminal step of RNA degradation

    Soo-Kyoung Kim, Justin D Lormand ... Vincent T Lee
    RNA degradation is completed through specific intermediates, such as diribonucleotides, which must be removed from the cells by a specific enzyme.
    1. Chromosomes and Gene Expression

    Identification of RBPMS as a mammalian smooth muscle master splicing regulator via proximity of its gene with super-enhancers

    Erick E Nakagaki-Silva, Clare Gooding ... Christopher WJ Smith
    By focusing on RNA-binding proteins whose genes have super enhancers in smooth muscle cells, the protein RBPMS was identified as an alternative splicing master regulator.
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Cryo-EM structures of remodeler-nucleosome intermediates suggest allosteric control through the nucleosome

    Jean Paul Armache, Nathan Gamarra ... Yifan Cheng
    Cryo-EM structures capture different conformational states of chromatin remodeler-nucleosome complexes.
    1. Developmental Biology

    Glycosylphosphatidylinositol biosynthesis and remodeling are required for neural tube closure, heart development, and cranial neural crest cell survival

    Marshall Lukacs, Tia Roberts ... Rolf W Stottmann
    Anchoring of proteins to the cell membrane through the glycosylphosphatidylinositol (GPI) anchor is critical for the survival of the cells that will give rise to the brain and face.
    1. Computational and Systems Biology

    Metabolic network percolation quantifies biosynthetic capabilities across the human oral microbiome

    David B Bernstein, Floyd E Dewhirst, Daniel Segrè
    A novel metabolic network analysis method enables large-scale computational predictions of biosynthetic capabilities across the human oral microbiome, revealing a unique cluster of fastidious microorganisms and potential metabolic interdependencies.
    1. Neuroscience

    Exercise-induced enhancement of synaptic function triggered by the inverse BAR protein, Mtss1L

    Christina Chatzi, Yingyu Zhang ... Gary L Westbrook
    Single episodes of voluntary exercise induced a functional increase in hippocampal synapses mediated by activity-dependent expression of the BAR protein Mtss1L, acting as a novel early effector of synapse formation.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Molecular organization and dynamics of the fusion protein Gc at the hantavirus surface

    Eduardo A Bignon, Amelina Albornoz ... Nicole D Tischler
    Hantavirus spikes are related laterally by 2-fold Gc contacts that can be disulfide-linked and display a temperature-dependent dynamic behavior at neutral pH, exposing and masking the Gc fusion loops.
    1. Cancer Biology
    2. Cell Biology

    Club cells form lung adenocarcinomas and maintain the alveoli of adult mice

    Magda Spella, Ioannis Lilis ... Georgios T Stathopoulos
    Airway cells are required for the maintenance of the adult mouse lung and for carcinogen-induced lung adenocarcinoma development, and are thus marked therapeutic targets.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Absolute quantification of cohesin, CTCF and their regulators in human cells

    Johann Holzmann, Antonio Z Politi ... Jan-Michael Peters
    Absolute quantification of cohesin, CTCF, NIPBL, WAPL and sororin in HeLa cells implies that some genomic cohesin and CTCF enrichment sites are unoccupied at any one time.