A spatial analysis of auditory and non-auditory properties of excitatory and inhibitory neurons in the mouse dorsal inferior colliculus defines the border between the lateral and the dorsal cortex.
Matthew Swire, Yuri Kotelevtsev ... Charles ffrench-Constant
Endothelin signalling, regulated by changes in neuronal activity associated with experience, influences the number of myelin sheaths formed by individual oligodendrocytes.
The archaeal MCM helicase can load in multiple orientations on DNA but translocation proceeds with a leading N-terminal domain, which affects double hexamer activation at origins of replication.
Amygdala/temporal-prefrontal cortex fibers are organised in separate amygdalofugal and uncinate bundles in humans and macaques, shaping the anatomical foundation for decision-making and socio-emotional behaviour.
Marisa A Yonemitsu, Rachael M Giersch ... Michael J Metzger
A transmissible cancer that arose in a marine mussel spread from a single animal to become a global pathogen affecting two other mussel species in both Europe and South America.
When an essential metabolic gene in E. coli is mutationally inactivated, subsequent evolution rarely reverts the mutation to wild type but rather follows unexpected paths that rewire metabolic fluxes.
Cassandra L Stowe, Thomas A Burley ... Martin A Pule
Two cellular populations can be tracked in the same small animal model using near-infrared bioluminescence imaging, for the first time opening up the window for multi-coloured bioluminescence.
Axelle Calcus, Outi Tuomainen ... Lorna F Halliday
Mild-to-moderate sensorineural hearing loss causes changes in the neurophysiological functioning that emerge during adolescence, as suggested by both cross-sectional and longitudinal designs.
