Browse our Research Articles

Disruption of TFEB and TFE3 results in diminished p53 signaling capacity and altered cell cycle regulation under genotoxic stress conditions.

The neural representation of perceived sucrose intensity was contained in the firing rate and spike-timing of a 'small' population of neurons distributed across the Insula and Orbitofrontal taste cortices.

Selfish genetic elements may either promote or prevent the evolution of reproductive barriers, depending on the extent of gene flow between species.

Random sequence RNA pools display an innate capacity for ligation and recombination, enabling them to “bootstrap” themselves towards higher compositional, informational and structural complexity.

Rotavirus infection induces phosphorylation and proteasomal degradation of MAVS to suppress host antiviral interferon signaling.

A parallel neuronal network architecture ensures control of basic feeding reflex circuits via integration of crossmodal sensory information to filter multiple biological events and enhance meaningful behavioral choice.

Histone-lysine N-methyltransferase SETD3 (NP_115609.2) was identified as the actin-specific histidine N-methyltransferase, an enzyme catalyzing the extremely well-conserved methylation of H73 in β-actin.

HIPPO signaling antagonizes the apical domain of polarized cells, driving cell internalization, regulated gene expression, and cell fate change during formation of pluripotent stem cell progenitors in the mouse embryo.

Extensive cytological and biochemical analyses show that the conserved Sf3A2 and Prp31 splicing factors bind microtubules and the Ndc80 complex, playing direct mitotic functions in both Drosophila and human mitosis.

Due to subunit-exchange, CaMKII can store information at diverse time-scales and might play a central role in the memory maintenance.