Browse our Research Articles

Page 988 of 1,403
    1. Neuroscience

    Acute control of the sleep switch in Drosophila reveals a role for gap junctions in regulating behavioral responsiveness

    Michael Troup, Melvyn HW Yap ... Bruno van Swinderen
    Optogenetic activation reveals a larger role for the fly brain 'sleep switch' neurons in controlling both waking and sleeping behavioral responsiveness, partly via a parallel channel involving innexin6 electrical synapses.
    1. Cell Biology

    Tryparedoxin peroxidase-deficiency commits trypanosomes to ferroptosis-type cell death

    Marta Bogacz, R Luise Krauth-Siegel
    Ferroptosis is an evolutionary ancient process that is counterbalanced by distant peroxidases, GPx4 in mammals and tryparedoxin peroxidases in trypanosomes, and can be induced at distinct subcellular membranes depending on the individual cell type.
    1. Cell Biology
    2. Developmental Biology

    Spatial and temporal analysis of PCP protein dynamics during neural tube closure

    Mitchell T Butler, John B Wallingford
    Planar cell polarity proteins display dynamic spatial and temporal patterns of enrichment that tightly correlate with myosin-dependent cell behaviors during neural tube closure.
    1. Immunology and Inflammation

    CCR7 defines a precursor for murine iNKT cells in thymus and periphery

    Haiguang Wang, Kristin A Hogquist
    Adoptive transfer and genetic manipulation revealed a previously unknown sub-population of PLZFhi CCR7+ iNKT cells as precursors for all three iNKT effector subsets in both thymus and periphery in mice.
    1. Evolutionary Biology

    Long read sequencing reveals poxvirus evolution through rapid homogenization of gene arrays

    Thomas A Sasani, Kelsey R Cone ... Nels C Elde
    An adaptive process of genetic homogenization in poxviruses facilitates the propagation of single nucleotide variation within gene copies and might favor the persistence of large gene copy arrays.
    1. Neuroscience

    A subcortical circuit linking the cerebellum to the basal ganglia engaged in vocal learning

    Ludivine Pidoux, Pascale Le Blanc ... Arthur Leblois
    The cerebellum sends a functional input to the song-related basal ganglia via the thalamus in songbirds that can modify premotor activity, and it participates to song learning in juvenile birds.
    1. Neuroscience

    Conservation of preparatory neural events in monkey motor cortex regardless of how movement is initiated

    Antonio H Lara, Gamaleldin F Elsayed ... Mark M Churchland
    Voluntary movements are preceded by a temporally flexible preparatory neural process that is present regardless of whether movement is initiated rapidly or thoughtfully.
    1. Neuroscience

    The adipocyte hormone leptin sets the emergence of hippocampal inhibition in mice

    Camille Dumon, Diabe Diabira ... Jean-Luc Gaiarsa
    Maternal obesity and excess of the adipocyte hormone leptin delays the emergence of synaptic inhibition in the developing brain mice.
    1. Ecology
    2. Epidemiology and Global Health

    Temperature explains broad patterns of Ross River virus transmission

    Marta Strecker Shocket, Sadie J Ryan, Erin A Mordecai
    Accounting for nonlinear responses to temperature is critical for accurately predicting how Ross River virus and other mosquito-borne diseases will respond to climate change and detecting the effects of temperature on disease transmission.
    1. Plant Biology

    The plant pathogen Pseudomonas aeruginosa triggers a DELLA-dependent seed germination arrest in Arabidopsis

    Hicham Chahtane, Thanise Nogueira Füller ... Luis Lopez-Molina
    Arabidopsis seed germination can be repressed by a Pseudomonas factor.