Browse our Research Articles

Page 992 of 1,403
    1. Physics of Living Systems

    Dynamic density shaping of photokinetic E. coli

    Giacomo Frangipane, Dario Dell'Arciprete ... Roberto Di Leonardo
    The concentration of motile bacteria, expressing a light-driven proton pump, can be precisely controlled in space and time by spatially modulating their swimming speeds with a structured light pattern.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Using paired serology and surveillance data to quantify dengue transmission and control during a large outbreak in Fiji

    Adam J Kucharski, Mike Kama ... Martin L Hibberd
    A combination of surveillance data, paired sera and mathematical modelling reveals which factors may influence dengue transmission and control in island settings.
    1. Neuroscience

    Stimulus vignetting and orientation selectivity in human visual cortex

    Zvi N Roth, David J Heeger, Elisha P Merriam
    Functional MRI measurements of orientation reflect coarse-scale biases that are wholly determined by second-order interactions between the stimulus aperture and the underlying orientation.
    1. Cancer Biology
    2. Immunology and Inflammation

    The newly-arisen Devil facial tumour disease 2 (DFT2) reveals a mechanism for the emergence of a contagious cancer

    Alison Caldwell, Rachel Coleby ... Hannah VT Siddle
    A recently discovered contagious cancer in the Tasmanian devil has the potential to become widespread in the population due to the loss of histocompatibility antigens that are allogeneic to its hosts.
    1. Cell Biology
    2. Developmental Biology

    Developmentally regulated H2Av buffering via dynamic sequestration to lipid droplets in Drosophila embryos

    Matthew Richard Johnson, Roxan Amanda Stephenson ... Michael Andreas Welte
    In early Drosophila embryos, histone H2Av continuously exchanges between cytoplasmic lipid droplets, a process that modulates H2Av import into nuclei and constitutes a novel post-translational strategy to regulate nuclear H2Av levels.
    1. Cell Biology

    Reactivation of RNA metabolism underlies somatic restoration after adult reproductive diapause in C. elegans

    Nikolay Burnaevskiy, Shengying Chen ... Matt Kaeberlein
    Morphological and functional rejuvenation upon exit from adult reproductive diapause in C. elegans is independent of germline signaling, but instead involves somatic nucleolar activation and expansion of the RNA pool.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Structural insights into the architecture and membrane interactions of the conserved COMMD proteins

    Michael D Healy, Manuela K Hospenthal ... Rajesh Ghai
    A structural basis for the assembly of core subunits of the Commander Complex has been discovered.
    1. Cell Biology

    Measuring NDC80 binding reveals the molecular basis of tension-dependent kinetochore-microtubule attachments

    Tae Yeon Yoo, Jeong-Mo Choi ... Daniel J Needleman
    Quantitative experiments and theory show that the tension-dependent regulation of NDC80 binding to kinetochore microtubules arises from a combination of the changing Aurora B concentration at NDC80 and the nonlinearity of Aurora B autoactivation.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Evolution of gene dosage on the Z-chromosome of schistosome parasites

    Marion A L Picard, Celine Cosseau ... Beatriz Vicoso
    An analysis of gene dosage at the DNA, RNA and protein level yields new insights into the early stages of Z-chromosome dosage compensation in schistosome parasites.
    1. Cell Biology
    2. Developmental Biology

    Radially patterned cell behaviours during tube budding from an epithelium

    Yara E Sanchez-Corrales, Guy B Blanchard, Katja Röper
    Quantitative analysis in quasi-3D reveals apically driven cell behaviours that are closely coordinated across the tissue to allow ordered tube invagination through a focal point.