Senescent cells release an arachidonic acid-derived electrophilic oxylipin that inhibits myoblast differentiation by covalent modification and activation of HRas.
Amber R Philp, Carolina R Reyes ... Francisco J Rivera
Transient platelet accumulation supports oligodendrocyte progenitor cell differentiation during myelin repair, while sustained exposure to elevated platelet numbers hampers the generation of remyelinating cells.
Adolescent brain development involves dopamine axon growth and a coincident change in UNC5c receptor expression, both of which are responsive, in unison, to an environmental signal.
The phosphorylation of FLS2 may activate flg22-triggered immunity by facilitating the partitioning of FLS2 into functional AtRem1.3-associated nanodomains.
High-resolution mapping of RNA polymerase II transcripts shows that the directionality of mammalian promoters is determined by preferential transcriptional initiation and the opposing activities of Integrator and CDK9.
This time-shortened work flow improves sensitivity and specificity for the identification of bacteria in bone infections independently of bacterial culturability.
The 'low water' agar assay provides a reliable and practical high-throughput method for studying plant molecular signaling responses to drought stress.
Weiting Zhang, Karl Petri ... Jing-Ruey Joanna Yeh
Strategic pegRNA designs and other approaches mitigating 5' and 3' interactions within pegRNAs can often lead to substantial improvements in prime editing efficiency.
