Computational pipeline SPICE systematically screens and predicts novel protein-protein binding complexes including the previously unrecognized global association and functional cooperation between IKZF1 and AP1.
Ablation of the G-protein-coupled receptor C3aR1 specifically on macrophages or Kupffer cells does not alter the course of metabolic dysfunction-associated steatotic liver disease in a dietary mouse model.
Distinct frequency-based interactions between cortical and subcortical regions highlight the cerebellum’s crucial role in speech production and perception.
Natalia Jagielska, Thomas G Kaye ... Michael Pittman
Laser-stimulated fluorescence (LSF) imaging of early pterosaurs uncovers new soft tissue data of tail vane that reveals sophisticated, dynamic tensioning usage and expands its evolutionary origins.
Benedikt M Mortzfeld, Shakti K Bhattarai, Vanni Bucci
12 new class IIb microcins have been structurally identified, phylogenetically assessed, and functionally tested for their antimicrobial activity, increasing the total number of these bacteriocins to 17.
Marie-Eve Picard, Miriam Kunz ... Pierre Rainville
Facial expression provides a complementary channel to communicate pain experiences and reflects the activation of brain mechanisms partly distinct from those associated with subjective self-reports of pain.
SLC35G1 is the first highly chloride-sensitive transporter localized on the basolateral membrane of intestinal epithelial cells, responsible for citrate absorption.