Browse our Short Reports

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    1. Ecology
    2. Microbiology and Infectious Disease

    Humanization of wildlife gut microbiota in urban environments

    Brian A Dillard et al.
    Urban wildlife harbor gut bacteria found in humans but missing from rural wildlife, consistent with bacterial transmission from humans to wildlife in cities.
    1. Plant Biology

    Perception of a conserved family of plant signalling peptides by the receptor kinase HSL3

    Jack Rhodes et al.
    Identification of a new family of stress-induced plant signalling peptides and their cognate receptor.
    1. Neuroscience

    A generalized cortical activity pattern at internally generated mental context boundaries during unguided narrative recall

    Hongmi Lee, Janice Chen
    Prominent transitions between different mental contexts produce a stereotyped brain state shared across internally and externally generated transitions but distinct from minor within-context transitions, potentially reflecting a major flushing and updating of mental models.
    1. Immunology and Inflammation
    2. Structural Biology and Molecular Biophysics

    Structure of the IL-27 quaternary receptor signaling complex

    Nathanael A Caveney et al.
    The cryogenic-electron microscopy structure of IL-27 bound to receptors, IL-27Rα and gp130, revealing a three-site assembly mechanism and overall topology and molecular details reminiscent of IL-6 but distinct from related IL-12 and IL-23.
    1. Ecology

    Regional opportunities for tundra conservation in the next 1000 years

    Stefan Kruse, Ulrike Herzschuh
    The treeline follows climate warming with a severe time lag, but migration rates are increasing so that only under ambitious mitigation efforts will 30% of original tundra areas remain in the north in the long run.
    1. Immunology and Inflammation
    2. Medicine

    The DNA sensors AIM2 and IFI16 are SLE autoantigens that bind neutrophil extracellular traps

    Brendan Antiochos et al.
    A novel extracellular role for cytoplasmic DNA sensors in shielding NET DNA from DNase-mediated degradation.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Genetic variation in ALDH4A1 is associated with muscle health over the lifespan and across species

    Osvaldo Villa et al.
    Leveraging the US Health and Retirement Study and C. elegans genetics reveals ALDH4A1/alh-6 as an evolutionarily conserved biomarker for normal muscle function over the lifespan.
    1. Developmental Biology
    2. Medicine

    VE-cadherin enables trophoblast endovascular invasion and spiral artery remodeling during placental development

    Derek C Sung et al.
    VE-cadherin is required for trophoblast invasion of the maternal decidua and spiral arteries.
    1. Developmental Biology
    2. Immunology and Inflammation

    A functional screen of RNA binding proteins identifies genes that promote or limit the accumulation of CD138+ plasma cells

    David J Turner et al.
    A genetic screening approach identifies RNA binding proteins that enhance or inhibit the accumulation of CD138+ plasma cells in vitro, and chimeric mouse models demonstrate that YTHDF2 promotes the accumulation of antibody secreting cells in vivo.
    1. Cancer Biology

    Detection of malignant peripheral nerve sheath tumors in patients with neurofibromatosis using aneuploidy and mutation identification in plasma

    Austin K Mattox et al.
    Detection of aneuploidy and/or mutations in ctDNA may represent a promising approach to detecting patients with MPNST.