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Lineage tracing and genetic analysis in zebrafish show that the pseudobranch is a serial homolog of the gills arising from the jaw-forming mandibular arch, thus supporting the model that vertebrate jaws derived from an ancestral mandibular gill.

Repressing astroglial PTBP1 by shRNA or antisense oligonucleotide fails to convert astrocyte to neuron including dopaminergic neuron in a 6-OHDA mouse model of PD.

Liquid biopsy methods utilizing brain-specific cell-free DNA methylation markers can detect brain cell death and potentially assist early detection and monitoring of schizophrenia.

Urban wildlife harbor gut bacteria found in humans but missing from rural wildlife, consistent with bacterial transmission from humans to wildlife in cities.

Identification of a new family of stress-induced plant signalling peptides and their cognate receptor.

Prominent transitions between different mental contexts produce a stereotyped brain state shared across internally and externally generated transitions but distinct from minor within-context transitions, potentially reflecting a major flushing and updating of mental models.

The cryogenic-electron microscopy structure of IL-27 bound to receptors, IL-27Rα and gp130, revealing a three-site assembly mechanism and overall topology and molecular details reminiscent of IL-6 but distinct from related IL-12 and IL-23.

The treeline follows climate warming with a severe time lag, but migration rates are increasing so that only under ambitious mitigation efforts will 30% of original tundra areas remain in the north in the long run.

A novel extracellular role for cytoplasmic DNA sensors in shielding NET DNA from DNase-mediated degradation.

Leveraging the US Health and Retirement Study and C. elegans genetics reveals ALDH4A1/alh-6 as an evolutionarily conserved biomarker for normal muscle function over the lifespan.