Browse our Short Reports

Page 3 of 24
    1. Neuroscience

    The human auditory brainstem response to running speech reveals a subcortical mechanism for selective attention

    Antonio Elia Forte et al.
    Selective attention to one of two speakers consistently modulates the response of the human auditory brainstem to each speaker's pitch.
    1. Chromosomes and Gene Expression
    2. Neuroscience

    Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in mice

    Mattia Volta et al.
    LRRK2 G2019S knock-in mice are a genetically faithful model that recapitulates the slow disease progression of familial PD, with initial alterations to behaviour and neurotransmission providing early pathophysiological targets for neuroprotective interventions.
    1. Chromosomes and Gene Expression
    2. Immunology and Inflammation

    Major transcriptional changes observed in the Fulani, an ethnic group less susceptible to malaria

    Jaclyn E Quin et al.
    Examining gene expression in the Fulani, an ethnic group relatively protected from malaria, identifies a more transcriptionally reactive response in cells of the innate immune system.
    1. Human Biology and Medicine
    2. Neuroscience

    Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI

    Martina Absinta et al.
    Meningeal lymphatic vessels are present in human and nonhuman primates (common marmoset monkeys) and they can be noninvasively imaged and mapped in vivo with high-resolution, clinical MRI.
    1. Developmental Biology and Stem Cells

    Lineage tracing of genome-edited alleles reveals high fidelity axolotl limb regeneration

    Grant Parker Flowers et al.
    CRISPR-based lineage tracing in the axolotl shows that regenerated limbs are composed of the same cell lineages in the same frequencies as those that gave rise to the original limb.
    1. Neuroscience

    Unusual prism adaptation reveals how grasping is controlled

    Willemijn D Schot et al.
    Adapting single-digit movements in opposite directions makes people open their grip in accordance with the adaptations of the individual digits, showing that grip aperture arises from goal-directed movements of the digits rather than being controlled independently.
    1. Neuroscience

    Thalamic input to auditory cortex is locally heterogeneous but globally tonotopic

    Sebastian A Vasquez-Lopez et al.
    Layers 1 and 3b/4 of auditory cortex receive surprisingly heterogeneous but tonotopically matching input from the thalamus.
    1. Neuroscience

    Aversive stimuli drive hypothalamus-to-habenula excitation to promote escape behavior

    Salvatore Lecca et al.
    Glutamatergic signaling from the lateral hypothalamus instructs lateral habenular neurons for encoding aversive external stimuli to subsequently guide escape behaviours.
    1. Biochemistry and Chemical Biology

    In vivo experiments do not support the charge zipper model for Tat translocase assembly

    Felicity Alcock et al.
    A prominent model for the structural organisation of the Tat (twin-arginine translocase) protein transport system fails live cell tests.
    1. Human Biology and Medicine
    2. Neuroscience

    Localization of spontaneous bursting neuronal activity in the preterm human brain with simultaneous EEG-fMRI

    Tomoki Arichi et al.
    Direct measure of neural and hemodynamic activity in the developing human brain shows that the insula is a major source of transient bursting events that are critical for cortical maturation.