Browse our Tools and Resources

Tools and resources to identify transcriptional regulators that create and maintain differences between photoreceptor subtypes.

Applying a CRISPR knockout screen in polarized intestinal epithelial cells and subsequent phenotypic analyses identified various genes, of which several were previously not associated with epithelial homeostasis, to be relevant for proper epithelial polarization, apical cargo transport, and endo/lysosomal morphology.

Conditions for multiplexed antibody labeling in mouse brain tissue translates to effective labeling in human brain tissue when samples are prepared similarly.

A collection of 22 nanobodies against 11 different Drosophila sarcomeric protein epitopes was generated, validated in stainings and for some transgenic fly lines were generated to monitor the dynamics of the sarcomeric proteins in muscles in vivo.

Automated computational unfolding of the hippocampus allows analyses at its mesoscale and facilitates novel discoveries in the study of cognition and disease.

Newly developed, highly active CRISPR interference single guide RNA libraries and effectors together enable high-quality genetic screens across cell models.

scatterHatch helps users generate colorblind-friendly scatter plot visualizations by using a combination of patterns and high-contrast colors to represent distinct point groups.

New functionality in RELION-4.0 allows convenient structure determination from cryo electron tomography data to resolutions sufficient for de novo atomic modelling.

Transcriptional analyses provide an atlas of how traumatic brain injury and aging shape meningeal cell composition and gene expression.

A software distributed platform for the Raspberry Pi to simplify and unify hardware access over the Ethernet network with almost real-time latencies.