Browse our Tools and Resources

Page 26 of 91
    1. Cell Biology

    Viscoelastic properties of suspended cells measured with shear flow deformation cytometry

    Richard Gerum, Elham Mirzahossein ... Ben Fabry
    Under fluid shear, living cells deform elliptically, align in flow direction, and rotate, from which their frequency-dependent viscoelastic properties can be inferred.
    1. Neuroscience

    Deep learning-based feature extraction for prediction and interpretation of sharp-wave ripples in the rodent hippocampus

    Andrea Navas-Olive, Rodrigo Amaducci ... Liset M de la Prida
    A new method is described to identify sharp-wave ripples from the rodent hippocampus with deep learning techniques, which may help to identify and characterize previously undetected physiological events.
    1. Developmental Biology
    2. Neuroscience

    EZ Clear for simple, rapid, and robust mouse whole organ clearing

    Chih-Wei Hsu, Juan Cerda III ... Joshua D Wythe
    With three simple steps in 48 hr, EZ Clear effectively renders adult mouse organs optically transparent while simultaneously preserving signal from synthetic and endogenous fluorescent reporters and is compatible with wholemount immunostaining and cryosectioning followed by histological or immunofluorescent staining.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Constructing an atlas of associations between polygenic scores from across the human phenome and circulating metabolic biomarkers

    Si Fang, Michael V Holmes ... Tom G Richardson
    A comprehensive resource to systematically evaluate the genetically predicted associations between 125 polygenic risk scores and 249 metabolic traits.
    1. Neuroscience

    The Neurodata Without Borders ecosystem for neurophysiological data science

    Oliver Rübel, Andrew Tritt ... Kristofer E Bouchard
    The NWB data language enables reproduction, interchange, and reuse of diverse neurophysiology data, and the design principles of NWB are generally applicable to enhance discovery across biology through data FAIRness.
    1. Neuroscience

    Putting perception into action with inverse optimal control for continuous psychophysics

    Dominik Straub, Constantin A Rothkopf
    A new method for analyzing continuous psychophysics experiments estimates not only perceptual uncertainty from tracking tasks but also action variability, intrinsic costs, and subjective internal models.
    1. Plant Biology

    Uncovering natural variation in root system architecture and growth dynamics using a robotics-assisted phenomics platform

    Therese LaRue, Heike Lindner ... José R Dinneny
    Advances in robotics-assisted plant handling and automated image analysis enables the characterization of root growth dynamics for Arabidopsis accessions at late stages of development and the association of these traits with genetic variation and climatic variables.
    1. Neuroscience

    Neuroscout, a unified platform for generalizable and reproducible fMRI research

    Alejandro de la Vega, Roberta Rocca ... Tal Yarkoni
    A web-based analysis platform for public fMRI data using naturalistic stimuli, leveraging state-of-the-art feature extraction models to enable more generalizable and reproducible findings.
    1. Neuroscience

    Fast, high-throughput production of improved rabies viral vectors for specific, efficient and versatile transsynaptic retrograde labeling

    Anton Sumser, Maximilian Joesch ... Yoav Ben-Simon
    Mapping neuronal circuits is made substantially faster, simpler and more accurate with this extended toolkit of novel cell lines and vectors.
    1. Computational and Systems Biology
    2. Neuroscience

    Reverse engineering of metacognition

    Matthias Guggenmos
    A model framework and toolbox to quantify metacognitive biases and sources of metacognitive noise in animal and human confidence data.