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A simple and robust statistical test for neuronal stimulus response, that outperforms PSTH-based approaches such as t-tests and ANOVAs.

Whole-brain quantitative input-output circuits of glutamatergic and GABAergic neurons in the mouse dorsal and median raphe nuclei were mapped using viral tracing and high-resolution optical imaging.

Single-nucleus transcriptomics exposes unique features of human somatosensory neurons and clues that may help resolve repeated problems in translating new experimental approaches for treating pain.

A knockin mouse line was made to label endogenous AMPA receptors, enabling direct observation of synaptic plasticity in behaving animals with single-synapse resolution across the entire brain.

A switch-like cell fate divergence revealed by continuous single-cell tracking during entry into quiescence.

Using single nucleus RNA sequencing, a complete catalogue of cell types was determined for the mouse iris, and this information was used as a starting point to define the effects of pupil dilation on gene expression and on nuclear morphology.

Methods for screening hundreds of DNA sequences for enhancer activity have been extended for use in vivo, uncovering novel enhancer elements active in the early postnatal brain.

DAS is a universal tool for segmenting and identifying acoustic signals in single and multi channel recordings robustly, reliably, and at low latency.

A unique toolbox of novel mouse lines expressing optical effectors and sensors in cardiovascular, smooth muscle, and additional lineages allows extensive in vivo and ex vivo analysis of complex biological systems.

The in vivo transcriptomic fingerprint encoding defective decidualization comprises 120 genes associated with an imbalance hormonal signaling in the decidual endometria of women who developed severe preeclampsia.