Browse our Tools and Resources

DExCon, LUXon, and DExogron approaches simultaneously block endogenous gene expression and permit tuning of re-expression levels in time and space; proof-of-principle reveals unforeseen differences in protein kinetics, cargo handling, and cell migration regulation between closely related Rab11 family members.

A physics-based, statistically rigorous mathematical model enables automated, objective interpretation of images from single-molecule fluorescence colocalization microscopy experiments.

Lead-OR visualizes results derived from microelectrode recordings in anatomical space, together with information derived from patient-specific MRI data, as well as high-resolution atlas resources during deep brain stimulation surgery.

MorphoGraphX is a user-friendly image processing software primarily aimed at segmenting 3D biological images into cells, quantifying cellular gene expression and growth, and understanding these data in the spatial context of developing organs.

NET-seq analysis of 41 S. cerevisiae transcription regulatory factors uncovers their differential and opposing effects on Pol II transcription elongation and antisense transcription, revealing that wild-type transcription is balanced by the joint impact of many regulators.

Via the capacitance clamp, electrophysiologists can for the first time flexibly set an artificial membrane capacitance for neurons and other excitable cells and thereby adjust their membrane time constant independent of any conductance changes.

The LOTUS initiative builds, through the Wikidata knowledge graph, a virtuous cycle of data sharing practices for natural products research.

A comprehensive excitatory projectome of the ventro-lateral prefrontal cortex in macaques was generated by using viral tracing integrated with serial two-photon tomography and diffusion tractography, thus providing new evidence of rejecting the monosynaptic connection of inferior fronto-occipital fasciculus in monkeys.

RNAseq profiles of female Aedes body parts, gut regions, and blood-fed guts provide insight into the anatomical patterning of immune and digestive function, and demonstrate the sequential induction of multiple peptidase cohorts over the course of blood meal digestion.

Integrative analysis of multi-tissue transcriptomics data of mice subjected to cold, mild warm or room temperature places the thermal adaptation of individual tissues in a whole-organism perspective.