Browse our Tools and Resources

A genetic method allows neurons to be individually identified and characterized by combining information about both their developmental origins and their mature patterns of gene expression.

Spizellomycespunctatusis a genetically tractable chytrid and model organism for comparative cell biology for understanding evolution of the cell cycle, actin dynamics, and cellularization in fungi and early eukaryotes.

A new analysis algorithm (DISC) enables accurate analysis of data from high-throughput single-molecule paradigms and reveals a non-cooperative binding mechanism of cyclic nucleotide-binding domains from HCN ion channels.

Fixed, intact animals of C. elegans can be physically expanded with high isotropy, to enable super-resolved imaging of general proteins and nucleic acids throughout the organism, on conventional microscopes.

The forces that multicellular tumor aggregates exert on their environment lead to non-linear, scale-invariant tissue deformations far away from the tumor, which can be exploited to quantify its collective contractility.

A new user-intervention-free classification, using single-fluorescent markers, measures conventionally unmeasureable phenotypes in early stages during clathrin-mediated endocytosis.

Analysis of periprotein lipids by direct extraction of membrane proteins, using styrene-maleic acid polymers.

Single-cell RNA-sequencing resolves the transcriptional landscape of asexual development in Toxoplasma gondii, revealing concerted genetic programs to Plasmodiumfalciparum and a novel transcriptional factor that controls antigen switching.

Generation of stable transgenic opsin lines together with in vivo calibration of their efficacy using behavioural and electrophysiological assays constitutes a novel optogenetic toolkit in zebrafish.

A fungal bioluminescence pathway can be reconstituted in planta to create luminescence in many plant species without external substrate addition, and be used to design customizable reporters of gene-expression.