A new imaging modality is described that can simultaneously record from several dishes without using robotics, which enables researchers to perform high-throughput, continuous measurements on biological samples.
A flexible and accurate methodology to fit reduced compartmental models to dendritic morphologies shows that models with very few compartments can capture many dendritic computations.
Julio D Perez, Susanne tom Dieck ... Erin M Schuman
Single somata and dendrites of individual rat neurons were laser-captured and sequenced to discover and compare the subcellular transcriptomes, identifying over 4000 mRNAs in GABAergic dendrites.
A new nomenclature convention for mammalian cell types utilizing shared taxonomies and quantitative cell features is applied to high-quality, open data from the mouse and human brain.
Florelle Domart, Peter Cloetens ... Richard Ortega
The development of high-resolution correlative imaging of metals and proteins reveals the interaction of copper and zinc with the synaptic architecture of neurons.
Antonio Cappuccio, Shane T Jensen ... Elena Zaslavsky
The immune Synergistic/Antagonistic Interaction Learner (iSAIL) resource has the capacity to generate insight into combinatorial immunity, help guide hypothesis generation and further experimentation relevant to basic research and drug therapeutics.
