Novel genetically encoded tools PFE3, paGFE3, and chGFE3 can be used to reversibly ablate excitatory synapses constitutively, and inhibitory synapses in a light- or chemically dependent manner.
Behavioral experiments provide strong evidence that krill swimming behavior is controlled by biological clocks throughout the year, revealing a key mechanism for adaptation to high-latitude habitats.
During aging, microglia progress through intermediate cellular states, including stress response and translation upregulation states, that modulate subsequent activation and impact cognitive decline.
To better understand how olfactory ensheathing cells modify spinal cord injury sites, single-cell RNA-sequencing was used to identify five OEC subtypes, progenitors, and novel genes associated with axonal outgrowth.
William Hockeimer, Ruo-Yah Lai ... James J Knierim
Place cells that show repeating place fields in geometrically similar locations of an environment modulate their firing rates differently in each field based on movement direction.
Valeria Sulzyk, Ludmila Curci ... Patricia S Cuasnicu
The identification of epididymal proteins relevant for sperm DNA integrity and early embryo development will contribute to a better understanding, diagnosis, and treatment of human infertility.