Browse the latest research

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    1. Biochemistry and Chemical Biology

    Multifaceted Functional Complexity of SARS-CoV-2 Helicase Nsp13 Underlies Its Integrated Motor and Remodeling Activities

    Hai-Hong Li, Jia-Li Hou ... Xi-Miao Hou
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    Modulating inter-mitochondrial contacts to increase membrane potential for mitigating blue light damage

    Yuxin Wang, Kangqiang Qiu ... Jiajie Diao
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    DEER of Singly Labelled Proteins to Evaluate Supramolecular Packing of Amyloid Fibrils

    Karen Tsay, Asif Equbal ... Yann Fichou
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology
    2. Microbiology and Infectious Disease

    In vitro sexual dimorphism establishment in schistosomes

    Remi Pichon, Magda E Lotkowska ... Gabriel Rinaldi
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Neuroscience

    How individual vigor shapes human–human physical interaction

    Dorian Verdel, Bastien Berret, Etienne Burdet
    Interactions between pairs of humans lead to the emergence of a dyadic vigor with similar characteristics as individual vigor, where both partners adapt, with the slower having a critical role.
    1. Neuroscience

    Alpha-band phase modulates perceptual sensitivity by changing internal noise and sensory tuning

    April Pilipenko, Alexandra McGowan, Jason Samaha
    Alpha-band, 8–13 Hz, neural oscillations phasically modulate the sensitivity of visual detection by changing internal sensory noise.
    1. Neuroscience

    Dimorphic neural network architecture prioritizes sexual-related behaviors in male Caenorhabditis elegans

    Xuebin Wang, Hanzhang Liu ... He Liu
    Graph theory and computational modeling reveal that neural network architecture biases the male Caenorhabditis elegans brain toward prioritized sexual behaviors.
    1. Structural Biology and Molecular Biophysics

    Structural mechanisms of pump assembly and drug transport in the AcrAB–TolC efflux system

    Xiaofei Ge, Zhiwei Gu, Jiawei Wang
    High‑resolution cryo‑EM structures uncover YbjP as a novel lipoprotein that positions TolC and supports conformational changes in E. coli drug efflux pumps mediating antibiotic resistance.
    1. Developmental Biology
    2. Genetics and Genomics

    The robust, high-throughput, and temporally regulated roxCre and loxCre reporting systems for genetic modifications in vivo

    Mengyang Shi, Jie Li ... Bin Zhou
    New mouse genetic tools, roxCre and loxCre, facilitate the study of gene function in cells of interest, allowing for simultaneous and efficient gene knockout and precise lineage tracing in vivo.