Browse the latest research

Page 4 of 1,908
    1. Microbiology and Infectious Disease

    A network perspective on the role of c-di-GMP-associated protein complexes in biofilm formation

    Marie-Francoise Noirot-Gros, Peter Larsen ... Philippe Noirot
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Sex differences in exploration–exploitation strategies during home-cage decision making

    Chantelle L Murrell, Alex A Legaria ... Alexxai V Kravitz
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    The Crunchometer, a low-cost, open-source acoustic analysis of feeding microstructure

    Elvi Gil Lievana, Benjamin Arroyo ... Ranier Gutierrez
    Making the moment-to-moment dynamics of solid-food intake measurable in any laboratory enables researchers to map the brain circuits that control appetite and accelerate the development of treatments for obesity.
    1. Structural Biology and Molecular Biophysics

    In silico design and validation of high-affinity RNA aptamers for SARS-CoV-2 comparable to neutralizing antibodies

    Yanqing Yang, Lulu Qiao ... Ruhong Zhou
    Computer-Aided Aptamer Modeling and Optimization (CAAMO) enables structure-guided RNA aptamer affinity maturation, producing a SARS-CoV-2 RBD (receptor binding domain) binder that rivals neutralizing antibodies and retains predicted activity across variants.
    1. Epidemiology and Global Health

    A natural experiment in Kenya reveals durable immunosuppressive effects of early childhood malaria: a longitudinal cohort study

    Mercy S Safari, Timothy O Makori ... Charles J Sande
    Early-life malaria exposure leaves a durable immunological imprint associated with reduced antibody responses to unrelated infections and vaccines.
    1. Chromosomes and Gene Expression

    Linking germline telomere removal to global programmed DNA elimination in Tetrahymena genome differentiation

    Kohei Nagao, Alix Lemoine ... Kazufumi Mochizuki
    Tetrahymena germline chromosome ends contain germline-limited sequences that are removed by chromosome breakage, a critical step for programmed DNA elimination of other germline-limited sequences and successful sexual reproduction.
    1. Neuroscience

    Relating layer fMRI signals to acoustics and intracranial neuronal activity in the human auditory cortex in a naturalistic design

    Hsin-Ju Lee, Jyrki Ahveninen ... Fa-Hsuan Lin
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Diverse paths for chemoreception in ciliated neurons contacting the cerebrospinal fluid in the spinal cord

    Emily Verran, Louise Moizan ... Claire Wyart
    Not revised
    Reviewed Preprint v1
    • Useful
    • Convincing
    • Incomplete
    1. Biochemistry and Chemical Biology

    A Membrane-Disruptive Action of VBIT-4 Challenges Its Role as a Widely Used VDAC1 Oligomerization Inhibitor

    Varun Ravishankar, Luís Borges-Araújo ... Lucie Bergdoll
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling