Browse the latest research

Page 5 of 1,913
    1. Cell Biology

    Centrosome Migration and Apical Membrane Formation in Polarized Epithelial Cells: Insights from the MDCK Cyst Model

    Po-Kai Wang, Keng-Hui Lin, Tang K Tang
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Efficient and reproducible pipelines for spike sorting large-scale electrophysiology data

    Alessio Paolo Buccino, Arjun Sridhar ... Joshua H Siegle
    Parallelized, cloud-compatible pipelines reduce spike sorting of large-scale neural recordings from weeks to hours, and enable systematic benchmarking of algorithms on hybrid data.
    1. Microbiology and Infectious Disease

    High-throughput quantification of population dynamics using luminescence

    Malte Muetter, Daniel C Angst ... Sebastian Bonhoeffer
    Tracking luminescent reporter light intensity is a fast, easy way to quantify population decline at high concentrations and tends to be a better proxy for biomass than for cell number.
    1. Neuroscience

    Boosting hyperalignment performance with age-specific templates

    Yuqi Zhang, Maria Ida Gobbini ... Ma Feilong
    Age-specific templates improve the quality of functional alignment using hyperalignment algorithms, and the improvement is consistent across age groups, validation analyses, and datasets.
    1. Microbiology and Infectious Disease

    Apparent cooperativity between human CMV virions introduces errors in conventional methods of calculating multiplicity of infection

    Christopher Peterson, Joshua Miller ... Vitaly V Ganusov
    Cooperation between individual virions of human cytomegalovirus at infecting cells leads to nonlinear scaling of cell infection probability with virion concentration.
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis

    Patrick B Jonker, Mumina Sadullozoda ... Alexander Muir
    Modeling the metabolic microenvironment of pancreatic tumors leads to the identification of polyunsaturated fatty acid metabolism as a vulnerability of pancreatic cancer.
    1. Cell Biology
    2. Neuroscience

    Engulfment by brain macrophages in a short-lived vertebrate

    Rahul Nagvekar, Angela N Pogson ... Anne Brunet
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Dense repeated sampling reveals impaired hierarchical integration of metacognitive confidence that scales with depression

    Paveen Phon-Amnuaisuk, Vanessa Teckentrup ... Claire M Gillan
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology
    2. Genetics and Genomics

    Multiple Molecular Pathways to Longevity: Opposing Gene Expression Programs Define Distinct Aging Strategies

    Zenith D Rudich, Jiaxi Guan ... Jeremy M Van Raamsdonk
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology
    2. Neuroscience

    Virtual reality reveals fine-scale alterations in behaviour following loss of the ADHD-linked gene adgrl3.1 in zebrafish

    Phoebe Reynolds, Emily Read ... Robert Hindges
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete