R Samuel Herron, Alexander K Kunisky ... Hun-Way Hwang
Genetics and biochemical analyses reveal an evolutionarily conserved mechanism to regulate gene isoform expression by mTORC1 and implicate possible gene isoform imbalance in cancer and neurological disorders with mTORC1 pathway dysregulation.
Visual crowding from clutter outside the limits of binocular fusion can still have a significant impact on object recognition and visual perception in the peripheral field.
Organoids are useful in studying guidance cues for retinal ganglion cell (RGC) axon generation and regeneration, and the method of RGC isolation via CNTN2 facilitates investigating RGC-related retinal diseases such as glaucoma.
In late 2021 and early 2022, many clinicians in Federally Qualified Health Centers (FQHCs) reported reduced cervical cancer screening and reported that pandemic-related staffing shortages impacted screening and follow-up.
Valerie Ann Perez, David W Sanders ... Marc I Diamond
Knockout of the J domain protein DnaJC7 reduces tau aggregate clearance and increases intracellular tau seeding for recombinant and human brain-derived tau seed sources.
Comparing the inflammatory proteome of healthy Tanzanian and Dutch adults highlights a pro-inflammatory phenotype and metabolic differences in Tanzanians, with the potential role of food-derived metabolites in driving inflammation.
When looking at another person shifting their gaze, humans use the gazer's head direction, velocity, and peripheral visual information to infer potential gaze goals and execute anticipatory eye movements.
Rtf2 is shown to associate with multiple splicing factors and influence splicing of a subset of introns explaining why previous work erroneously assigned it as a replication restart factor in fission yeast.