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Phylogenomics reveals the timeline over which marine bacteria and archaea colonized the oceans and shows the geological context of their diversification.

Candida albicans cells respond in two distinct ways to fluconazole exposure where cells enter the Ribo-dominant state characterized by an upregulation of ribosomal-related proteins and processes, or cells enter the Stress-dominant state characterized by the upregulation of stress responses.

Modeling the evolution of PRDM9 in light of recent results implicating the importance of PRDM9 binding symmetry suggests the advantage of new PRMD9 alleles is in limiting the number of binding sites used effectively rather than increasing net binding.

Identification of Cl⁻-induced folding advances the field’s understanding of prestin’s unique voltage-sensing mechanism and its involvement in mammalian hearing sensation.

Multidimensional study of signaling pathways and epigenomics investigates how TCR (T cell receptor) signaling and chromatin landscape interpaly and impact on Treg stability.

Massive IgG and IgA antibody deposition in severe alcoholic hepatitis livers, targeting unique human proteins and exhibiting hepatocyte killing potential, suggests a role for cross-reactive anti-bacterial antibodies in severe alcoholic hepatitis pathogenesis.

Prior expectations about the state of the sensory environment are dynamically updated in a context-dependent manner and selectively bias the build-up of human motor cortical activity during subsequent decisions.

Ultrasound promotes release of extracellular vesicles from cultured myotubes and elicits anti-inflammatory effects on macrophages, indicating the potential of ultrasound stimulation to muscle for anti-inflammatory purposes.

A novel FRET approach suggests that the intracellular termini of acid-sensing ion channel 1a do not form a complex at rest requiring a new hypothesis for ASIC1a involvement in stroke.

Clearance of engineered Salmonella which trigger regulated cell death is dependent upon the cellular 'bucket list,' which is determined both by cell death signaling pathway and by cell type infected.