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Page 481 of 1,892
    1. Immunology and Inflammation

    De novo fatty-acid synthesis protects invariant NKT cells from cell death, thereby promoting their homeostasis and pathogenic roles in airway hyperresponsiveness

    Jaemoon Koh, Yeon Duk Woo ... Doo Hyun Chung
    The development and functionalities of invariant natural-killer T cells are dependent upon their cell-intrinsic ACC1-mediated de novo fatty acid synthesis, which greatly affect outcomes of allergic asthma.
    1. Computational and Systems Biology
    2. Structural Biology and Molecular Biophysics

    Myristoyl’s dual role in allosterically regulating and localizing Abl kinase

    Svenja de Buhr, Frauke Gräter
    The cellular membrane competes with Abl for myristoyl binding to stabilize the preactivated state and enhance allosteric activation.
    1. Neuroscience

    Auditory cortical error signals retune during songbird courtship

    Caleb Jones, Jesse H. Goldberg
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    Menopause, Brain Anatomy, Cognition and Alzheimer’s Disease

    Manuela Costantino, Grace Pigeau ... M. Mallar Chakravarty
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Developmental Biology

    A human mitofusin 2 mutation can cause mitophagic cardiomyopathy

    Antonietta Franco, Jiajia Li ... Gerald W Dorn
    A rare human mitofusin (MFN) 2 mutation that uniquely impaired Parkin-mediated mitophagy evoked developmental heart disease and increased myocardial sensitivity to doxorubicin in mice, differentiating it from mitophagy-competent MFN2 mutations that cause neuropathy and implicating mitophagy in clinical cardiomyopathy.
    1. Structural Biology and Molecular Biophysics

    Structural basis of EHEP-mediated offense against phlorotannin-induced defense from brown algae to protect akuBGL activity

    Xiaomei Sun, Yuxin Ye ... Min Yao
    A structural and biochemical study reveals the molecular mechanism of the predator–prey associations of Aplysia kurodai and brown algae (akuBGL–phlorotannin/laminarin–EHEP system), which has high-potential applications in the biotechnology industry.
    1. Neuroscience

    Brain-imaging evidence for compression of binary sound sequences in human memory

    Fosca Al Roumi, Samuel Planton ... Stanislas Dehaene
    Humans memorize structured sound sequences using a language-of-thought compression algorithm.
    1. Neuroscience

    Mega-scale movie-fields in the mouse visuo-hippocampal network

    Chinmay Purandare, Mayank Mehta
    Neurons in the mouse hippocampus, known as place cells, surprisingly show movie-fields, where they reliably encode distinct segments of a black-and-white, silent movie, even without any task demand or rewards.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Autoinhibited kinesin-1 adopts a hierarchical folding pattern

    Zhenyu Tan, Yang Yue ... Michael A Cianfrocco
    Modular folding of kinesin-1 motor proteins enables a fully autoinhibited state.
    1. Neuroscience

    Experimentally induced active and quiet sleep engage non-overlapping transcriptional programs in Drosophila

    Niki Anthoney, Lucy Tainton-Heap ... Bruno van Swinderen
    Different methods for inducing sleep in Drosophila flies may be promoting distinct sleep stages with different functions when brain activity and gene expression are compared.