Browse the latest research

Page 480 of 1,892
    1. Neuroscience

    Competing neural representations of choice shape evidence accumulation in humans

    Krista Bond, Javier Rasero ... Timothy Verstynen
    Interactions between cortical and subcortical circuits in the mammalian brain flexibly control the flow of information streams that drive decisions by shifting the balance of power both within and between action representations.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Vibrio cholerae’s ToxRS bile sensing system

    Nina Gubensäk, Theo Sagmeister ... Tea Pavkov-Keller
    The sensory regulatory system of the cholera causative involves the detection of bile acids by direct interaction with the inner membrane protein complex formed by ToxR and ToxS, thereby inducing concentration-dependent structural changes.
    1. Cell Biology

    Independent regulation of Z-lines and M-lines during sarcomere assembly in cardiac myocytes revealed by the automatic image analysis software sarcApp

    Abigail C Neininger-Castro, James B Hayes ... Dylan Tyler Burnette
    Software is introduced for the rapid and comprehensive quantification of sarcomere-containing myofibrils and their precursors in cardiac myocytes, aiding in the advancement of cardiovascular cell biology investigations.
    1. Neuroscience

    Awake responses suggest inefficient dense coding in the mouse retina

    Tom Boissonnet, Matteo Tripodi, Hiroki Asari
    Retinal visual response properties in awake mice are similar to those under anesthesia or ex vivo, but not exactly the same, so knowledge of retinal function cannot be simply translated from ex vivo to in vivo.
    1. Structural Biology and Molecular Biophysics

    Pathologic polyglutamine aggregation begins with a self-poisoning polymer crystal

    Tej Kandola, Shriram Venkatesan ... Randal Halfmann
    The disease-associated aggregation of polyglutamine begins in a single molecule with a specific structure.
    1. Neuroscience

    ChatGPT identifies gender disparities in scientific peer review

    Jeroen PH Verharen
    Generative artificial intelligence, such as OpenAI’s ChatGPT, can be used to analyze scientific texts with specialized constructions, including peer review reports.
    1. Neuroscience

    History information emerges in the cortex during learning

    Odeya Marmor, Yael Pollak ... Ariel Gilad
    As mice learn a sensory discrimination task, information from the previous trial emerges during the current trial period in several task-related cortical areas, just before and during the sensation period.
    1. Neuroscience

    Motor actions are spatially organized in motor and dorsal premotor cortex

    Nicholas G Chehade, Omar A Gharbawie
    The spatial dimension of neural activity is an organizing feature of the neural code that controls motor actions.
    1. Cell Biology
    2. Medicine

    Increase of cell surface vimentin is associated with vimentin network disruption and subsequent stress-induced premature senescence in human chondrocytes

    Jana Riegger, Rolf E Brenner
    Disruption of the intracellular vimentin network upon cellular stress results in enhanced cell surface vimentin on human osteoarthritic chondrocytes and might represent a novel membrane-associated marker of stress-induced premature senescence.
    1. Cancer Biology
    2. Epidemiology and Global Health

    Risk of second primary cancers after a diagnosis of first primary cancer: A pan-cancer analysis and Mendelian randomization study

    Xiaohao Ruan, Da Huang ... Rong Na
    A certain type of primary cancer may cause another second primary cancer which would be of clinical importance to make a personalized screening plan for certain primary cancer patients.