Browse the latest research

Page 6 of 1,884
    1. Cell Biology

    Orderly mitosis shapes interphase genome architecture

    Krishnendu Guin, Adib Keikhosravi ... Tom Misteli
    High-throughput CRISPR-KO imaging screens reveal that disruption of mitotic processes impairs spatial genome organization in daughter cells.
    1. Cell Biology

    Prior cocaine use disrupts identification of hidden states by single units and neural ensembles in orbitofrontal cortex

    Wenhui Zong, Lauren Mueller ... Geoffrey Schoenbaum
    Rats with a history of cocaine use exhibited prolonged encoding of idiosyncratic task features in orbitofrontal cortex and a reduced ability to compress such features to identify underlying hidden states.
    1. Microbiology and Infectious Disease

    Antibiotic potentiation and inhibition of cross-resistance in pathogens associated with cystic fibrosis

    Nikol Kadeřábková, R Christopher D Furniss ... Despoina AI Mavridou
    Targeting disulfide bond formation disables multiple antibiotic resistance mechanisms and prevents cross-protection between pathogens associated with cystic fibrosis lung infections, restoring antibiotic efficacy in polymicrobial settings.
    1. Chromosomes and Gene Expression
    2. Immunology and Inflammation

    The long non-coding RNA Dreg1 is required for optimal ILC2 development

    Sara Quon, Adelynn Tang ... Rhys S Allan
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Evolutionary Biology

    New insights into the evolution of spider silk proteins illuminated by long-read transcriptomes

    Kesen Zhu, Shiyi Zhou ... Hui Xiang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    Modulating inter-mitochondrial contacts to increase membrane potential for mitigating blue light damage

    Yuxin Wang, Kangqiang Qiu ... Jiajie Diao
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology

    Cellular basis of accelerated whole-tooth regeneration

    Talha Mubeen, Haowen He ... Jeffrey T Streelman
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Developmental Biology
    2. Evolutionary Biology

    The endoderm cell trajectory of urochordate Styela clava reveals the dual developmental origin and evolution of digestive tract

    Yonghang Ge, Wei Zhang ... Jiankai Wei
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Developmental Biology
    2. Genetics and Genomics

    In situ mutational screening and CRISPR interference define apterous cis-regulatory inputs during compartment boundary formation

    Gustavo Aguilar, Michèle Sickmann ... Martin Müller
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Towards a unified molecular mechanism for ligand-dependent activation of NR4A-RXR heterodimers

    Xiaoyu Yu, Yuanjun He ... Douglas J Kojetin
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
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