Browse the latest research

Page 6 of 1,837
    1. Neuroscience

    The influence of nucleus accumbens shell D1 and D2 neurons on outcome-specific Pavlovian instrumental transfer

    Octavia Soegyono, Elise Pepin ... Vincent Laurent
    Cell-specific manipulations uncover novel mechanisms in the ventral striatum that mediate the influence of environmental stimuli on action selection.
    1. Biochemistry and Chemical Biology

    Membrane-mimetic thermal proteome profiling (MM-TPP) toward mapping membrane protein–ligand dynamic interactions

    Rupinder Singh Jandu, Ashim Bhattacharya ... Franck Duong van Hoa
    Peptidisc-based thermal proteome profiling enables detergent-free mapping of membrane protein–ligand interactions, advancing the discovery of druggable targets in membrane-mimetic environments.
    1. Cell Biology

    Calcium transfer from the ER to other organelles for optimal signaling in Toxoplasma gondii

    Zhu-Hong Li, Beejan Asady ... Silvia NJ Moreno
    In Toxoplasma gondii, SERCA-driven ER Ca²⁺ uptake sustains homeostasis and enables redistribution to mitochondria and other organelles, highlighting the ER as a central hub in parasite Ca²⁺ signaling and infection.
    1. Neuroscience

    Neural Correlates and Reinstatement of Recent and Remote Memory: A Comparison Between Children and Young Adults

    Iryna Schommartz, Philip F Lembcke ... Yee Lee Shing
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Incomplete
    1. Cancer Biology

    PTEN restrains SHH medulloblastma growth through cell autonomous and nonautonomous mechanisms

    Zhimin Lao, Salsabiel El Nagar ... Alexandra L Joyner
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology
    2. Physics of Living Systems

    The titin N2A-MARP signalosome constrains muscle longitudinal hypertrophy in response to stretch

    Robbert van der Pijl, Jochen Gohlke ... Coen Ottenheijm
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cancer Biology

    Therapeutic benefits of maintaining CDK4/6 inhibitors and incorporating CDK2 inhibitors beyond progression in breast cancer

    Jessica Armand, Sungsoo Kim ... Hee Won Yang
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Cell Biology

    Acidocalcisome-like vacuoles constitute a feedback-controlled phosphate buffering system for the cytosol

    Samuel Bru, Lydie Michaillat Mayer ... Andreas Mayer
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Ecology

    Early experience affects foraging behavior of wild fruit bats more than their original behavioral predispositions

    Adi Rachum, Lee M Harten ... Yossi Yovel
    Early-life environment shapes how wild bats behave as adults, showing that developmental experience, rather than innate predisposition, drives individual differences in foraging behavior.
    1. Genetics and Genomics

    Independent validation of transgenerational inheritance of learned pathogen avoidance in Caenorhabditis elegans

    Aalimah Akinosho, Joseph Alexander ... Andres Gabriel Vidal-Gadea
    Independent replication confirms that avoidance of pathogenic PA14 learned by Caenorhabditis elegans persists through the F2 generation using standardized sodium azide immobilization choice assays, clarifying prior reproducibility concerns.