Browse the latest research

Page 6 of 1,913
    1. Neuroscience

    Thalamo-accumbal circuit adaptations following extended oxycodone abstinence

    Yanaira Alonso Caraballo, Yan Li ... Elena Chartoff
    Prolonged oxycodone abstinence strengthens paraventricular thalamus to nucleus accumbens shell glutamatergic transmission in both sexes, yet only females show enhanced relapse, dissociating shared synaptic plasticity from sex-specific relapse vulnerability.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Methylation clocks fail to generalize across genetically admixed individuals

    Sebastián Cruz-Gonzalez, Ogechukwu Okpala ... John A Capra
    DNA-methylation-based predictors of biological age often fail to generalize across human populations, limiting their utility as biomarkers of aging and disease.
    1. Microbiology and Infectious Disease

    Niche exclusion of a lung pathogen in mice with designed probiotic communities

    Kelsey E Hern, Ashlee M Phillips ... Adam P Arkin
    Probiotic communities designed to inhibit a lung pathogen through niche exclusion show promise as a novel method of preventing respiratory infection.
    1. Neuroscience

    Deletion of neuroligins from astrocytes does not detectably alter synapse numbers or astrocyte cytoarchitecture by maturity

    Samantha Rose Golf, Justin H Trotter ... Thomas C Südhof
    Genetic deletions in mouse models and human neuron co-cultures reveal that astrocytic neuroligins are dispensable for synapse formation and maintenance of normal astrocyte morphology, suggesting neuroligins serve alternative, unidentified roles.
    1. Neuroscience

    Flexible brain state engagement predicts cognitive control transdiagnostically

    Jean Ye, Saloni Mehta ... Dustin Scheinost
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Targeting tankyrase scaffolding in the β-catenin destruction complex by PROTAC overcomes the limitation of catalytic inhibitors in cancer

    Qian Wang, Liping Li ... Chuo Chen
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Rapid cortical reorganization tracks goal-directed sensorimotor learning in real time

    Anthony Renard, Georgios Foustoukos ... Carl CH Petersen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Neuroscience

    Split-trial analysis reveals the information capacity of neural population codes

    Dylan Le, Xue-Xin Wei
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology
    2. Cancer Biology

    RAB14-dependent tubulovesicular recycling directs MET to invadopodia, promoting TNBC cell invasion

    Amrita Khamari, Atreyee Guria ... Sunando Datta
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Demonstrating the ability of GABAergic cells in the zona incerta to modulate motivation

    Laura Korobkova, Brian G Dias
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
Newer Older