Massimiliano Semeraro, Giuseppe Negro ... Davide Marenduzzo
In a polymer model of chromatin that explicitly incorporates different types of transcription factors, both specialised and mixed factories emerge naturally, with their composition governed by their size.
The loss of FMRP does not affect how neuronal ribosomes are stalled or where they are stalled, but reduces the number of neuronal RNA granules that contain stalled ribosomes.
RNA differentially regulates the assembly pathways of bacterial and host α-helical peptides, revealing supramolecular architecture as a tunable determinant of cytotoxic and antimicrobial function.
