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Page 6 of 1,911
Neuroscience
Identifying molecular instructions to hard-wire a sensory neuron’s synaptic connectivity
Júnia Vieira dos Santos, Renee Yin Yu ... Brian E Chen
Medicine
Immunology and Inflammation
TLR4 signaling drives tissue inflammation, Claudin-5 internalization, and vascular barrier breakdown in a mouse model of neonatal meningitis
Philip V Seegren, Amir Rattner ... Jeremy Nathans
Developmental Biology
Junctional β-Catenin Stabilization Links Wnt Signaling and Force Generation
Agimaa Otgonbaatar, Sujithra Shankar ... Nicholas S Tolwinski
Computational and Systems Biology
Permute-match tests detect significant correlations between time series despite nonstationarity and limited replicates
Alex E Yuan, Wenying Shou
Cell Biology
CROP2, a Retriever–PROPPIN complex mediating protein export from endosomes to the plasma membrane in human cells
Maria Giovanna De Leo, Andreas Mayer
Endosomes operate several exit routes that sort protein cargo and depend on pathway-specific associations of a PROPPIN with the responsible protein coat, such as the here identified CROP2, to support the departure of the cargo carriers.
Developmental Biology
Genetics and Genomics
Multiple Molecular Pathways to Longevity: Opposing Gene Expression Programs Define Distinct Aging Strategies
Zenith D Rudich, Jiaxi Guan ... Jeremy M Van Raamsdonk
Neuroscience
Excitation–inhibition balance controls coupling stability and network reorganization in a plastic Kuramoto model
Satoshi Kuroki, Kenji Mizuseki
Cancer Biology
JAK-STAT Pathway Heterogeneity Governs Immunotherapy Response in Breast Cancer
Jianbo Zhou, Heng Zhang ... Fu Peng
Cell Biology
Defective Neuronal Differentiation in Lowe Syndrome is Associated with Mitochondrial Dysfunction and Impaired Cilia-related Sonic Hedgehog Signaling
Grzegorz Walkiewicz, Siyu Chen ... Yang Sun
Medicine
Estimating bone marrow adiposity from head MRI and identifying its genetic architecture
Tobias Kaufmann, Pål Marius Bjørnstad ... Timothy Hughes
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