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The intrinsic factor of cell senescence, PCBP2, was identified by unlabeled quantitative proteomics, and its biological role in in vitro replication senescence of human bone marrow mesenchymal stromal cells was characterized in vitro.

Healthy lifestyle changes, particularly improvements in diet and smoking, were inversely related to comprehensive and organ-specific biological aging in Southwest China, highlighting key intervention targets to limit aging.

Multi-dimensional social relationships dynamically shape attentional biases toward in-group and out-group conspecifics in monkeys, with oxytocin modulating these interactions to reveal neurobiological links between social networks and visual information processing.

Plectin drives hepatocellular carcinoma progression and metastasis through cytoskeletal reorganization and oncogenic signaling, making it a promising therapeutic target for overcoming therapy resistance.

The ThermoMaze behavioral paradigm enables the collection of extensive physiological data while animals remain at distinct experimenter-controlled locations during rest.

UNC-6/Netrin functions both as a short-range adhesive cue and a gradient to guide axons in vivo.