Browse the latest research

Page 6 of 1,846
    1. Structural Biology and Molecular Biophysics

    Twelve phosphomimetic mutations induce the assembly of recombinant full-length human tau into paired helical filaments

    Sofia Lövestam, Jane L Wagstaff ... Sjors HW Scheres
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Convincing
    1. Developmental Biology

    Junctional and Actomyosin Dynamics Drive Endothelial Cell Rearrangements during Vascular Tube Formation

    Ludovico Maggi, Jianmin Yin ... Heinz-Georg Belting
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Developmental Biology
    2. Neuroscience

    Biophysical basis for brain folding and misfolding patterns in ferrets and humans

    Gary PT Choi, Chunzi Liu ... L Mahadevan
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Direct lineage conversion of postnatal mouse cortical astrocytes to oligodendrocyte lineage cells

    Justine Bajohr, Erica Y Scott ... Maryam Faiz
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Cancer Biology
    2. Evolutionary Biology

    Punctuated mutagenesis promotes multi-step evolutionary adaptation in human cancers

    Christopher Graser, Wenbo Wu ... Franziska Michor
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Cancer Biology

    Multimodal single-cell analyses reveal distinct fusion-regulated transcriptional programs in Ewing sarcoma

    Olivia G Waltner, April A Apfelbaum ... Scott N Furlan
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Neural correlates and reinstatement of recent and remote memory in children and young adults

    Iryna Schommartz, Philip F Lembcke ... Yee Lee Shing
    Children show less robust memory retention overnight and after 2 weeks, with memories transforming more rapidly from detailed to gist-like neural representations, revealing less stable consolidation mechanisms than in adults.
    1. Evolutionary Biology

    Trained immunity and immune priming in plants and invertebrates

    Joachim Kurtz, Raul Andino ... Jurriaan Ton
    An evolutionary perspective on immune priming across plants and invertebrates highlights the roles of microbiomes and epigenetic regulation in shaping innate immune memory with promising applications in agriculture and aquaculture.
    1. Cell Biology
    2. Developmental Biology

    Characterisation of cell-scale signalling by the core planar polarity pathway during Drosophila wing development

    Alexandre Carayon, Helen Strutt, David Strutt
    Quantitative Drosophila pupal wing experiments support planar polarity depending on cell-scale signalling that does not involve depletion of a limited pool of core proteins or polarised transport on microtubules.
    1. Neuroscience

    Sex differences in BNST signaling and BNST CRF in fear processing

    Olivia J Hon, Sofia Neira ... Thomas L Kash
    Critical differences in how the BNST responds to different types of fear across male and female mice.