Browse the latest research

Page 6 of 1,875
    1. Cancer Biology

    Blocking SHP2 benefits FGFR2 inhibitor and overcomes its resistance in FGFR2-amplified gastric cancer

    Yue Zhang, Hanbing Wang ... Yue Wang
    Dual blocking SHP2 and FGFR2 can not only promote the targeted tumor-killing effects and overcome FGFR2 inhibitor resistance caused by feedback activation, but also activate T cell-mediated anti-tumor immunity.
    1. Neuroscience

    Control of innate olfactory valence by segregated cortical amygdala circuits

    James R Howe, Chung Lung Chan ... Cory M Root
    Topographically distributed plCoA populations direct innate olfactory responses by signaling to divergent valence-specific targets, linking upstream olfactory identity to downstream valence behaviors, through a population code.
    1. Neuroscience

    Alcohol attenuates CRF-induced excitatory effects from the extended amygdala to dorsostriatal cholinergic interneurons

    Amanda Essoh, Xueyi Xie ... Jun Wang
    Stress-related corticotropin-releasing factor signaling directly modulates striatal cholinergic circuits, and alcohol exposure disrupts this control, revealing a circuit mechanism linking stress, alcohol use, and impaired behavioral flexibility.
    1. Neuroscience

    A stress-activated neuronal ensemble in the supramammillary nucleus produces anxiety-like behavior in male mice

    Jinming Zhang, Kexin Yu ... Jing Han
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Updating the sulcal landscape of the human lateral parieto-occipital junction provides anatomical, functional, and cognitive insights

    Ethan H Willbrand, Yi-Heng Tsai ... Kevin S Weiner
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Compelling
    1. Neuroscience

    Early Sleep-Dependent Sensory Gating in the Olfactory System

    Diego Serantes, Diego Gallo ... Matías Cavelli
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience
    2. Computational and Systems Biology

    High frequency spike inference with particle Gibbs sampling

    Giovanni Diana, B Semihcan Sermet ... David A DiGregorio
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Structural Biology and Molecular Biophysics

    A Structural Code for Assembly Specificity in GID/CTLH-Type E3 Ligases

    Pia Maria van gen Hassend, Hermann Schindelin
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Neuropeptidergic circuit modulation of developmental sleep in Drosophila

    Chikayo Hemmi, Kenichi Ishii ... Kazuo Emoto
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing