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    1. Chromosomes and Gene Expression

    Ligand-dependent Enhancer Activation Indirectly Modulates Non-target Promoters in a Chromatin Domain

    Darshika Bohra, Zubairul Islam ... Dimple Notani
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Solid
    1. Biochemistry and Chemical Biology

    Single-step in vitro reconstitution of the Escherichia coli ribosome mediated by two GTPase factors, EngA and ObgE

    Aya Sato, Weng Yu Lai ... Yoshihiro Shimizu
    A multi-step ribosome assembly method involving changes in ion concentration and temperature can now be carried out in a single step using the two GTPase factors, EngA and ObgE.
    1. Microbiology and Infectious Disease
    2. Neuroscience

    Enterovirus D68 2A protease causes nuclear pore complex dysfunction and independently contributes to motor neuron toxicity

    Katrina M Zinn, Mathew W McLaren ... Matthew J Elrick
    Enterovirus D68, a cause of acute flaccid myelitis, disrupts the composition and function of the nuclear pore complex primarily through its 2A protease, which is also toxic to motor neurons.
    1. Ecology

    Retraction: Exogenous myristate fuels the growth of symbiotic arbuscular mycorrhizal fungi but disrupts their carbon-phosphorus exchange with host plants

    Hanwen Chen, Tian Xiong ... Yutao Wang
    1. Neuroscience

    Developmental oligodendrocytes regulate brain function through the mediation of synchronized spontaneous activity

    Ryo Masumura, Kyosuke Goda ... Naofumi Uesaka
    Disrupting oligodendrocytes during a narrow early-life window leaves cerebellar circuits permanently mistimed, but adult re-synchronization restores social and motor behavior.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Constraints on the G1/S transition pathway may favor selection of multicellularity as a passenger phenotype

    Tom Louis Ducrocq, Damien Laporte, Bertrand Daignan-Fornier
    A genetic analysis in yeast establishes that multicellularity can arise as a side-effect (passenger phenotype) of a completely independent fitness advantage unrelated to the benefits of group formation itself.
    1. Cell Biology

    FMRP Regulates Neuronal RNA Granules Containing Stalled Ribosomes, Not Where Ribosomes Stall

    Jewel T-Y Li, Mehdi Amiri ... Wayne S Sossin
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Plant Biology

    Story about honest mistakes: The cyanobacterium Synechocystis has a promiscuous Entner-Doudoroff (ED) aldolase but no functional ED pathway

    Ravi Shankar Ojha, Marius Theune ... Kirstin Gutekunst
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Cell Biology
    2. Developmental Biology

    The Par complex regulates apical-basal cell polarity through modulation of FAK signaling homeostasis

    Meiai He, Lining Liang ... Hui Zheng
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    Improved cryo-EM reconstruction of sub-50 kDa complexes using 2D template matching

    Kexin Zhang, Timothy Grant, Nikolaus Grigorieff
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Incomplete
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