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Page 6 of 1,909
    1. Cell Biology

    Decoupling AMPK from fatty acid synthesis allows maintenance of fitness late in life

    Hanane Hadj-Moussa, Megan Ulusan ... Jonathan Houseley
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease
    2. Epidemiology and Global Health

    The age and sex dynamics of heterosexual HIV transmission in Zambia: an HPTN 071 (PopART) phylogenetic and modelling study

    Matthew Hall, William Probert ... the HPTN 071 (PopART) study team
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Epidemiology and Global Health

    A natural experiment in Kenya reveals durable immunosuppressive effects of early childhood malaria: a longitudinal cohort study

    Mercy S Safari, Timothy O Makori ... Charles J Sande
    Early-life malaria exposure leaves a durable immunological imprint associated with reduced antibody responses to unrelated infections and vaccines.
    1. Chromosomes and Gene Expression

    Linking germline telomere removal to global programmed DNA elimination in Tetrahymena genome differentiation

    Kohei Nagao, Alix Lemoine ... Kazufumi Mochizuki
    Tetrahymena germline chromosome ends contain germline-limited sequences that are removed by chromosome breakage, a critical step for programmed DNA elimination of other germline-limited sequences and successful sexual reproduction.
    1. Structural Biology and Molecular Biophysics

    In silico design and validation of high-affinity RNA aptamers for SARS-CoV-2 comparable to neutralizing antibodies

    Yanqing Yang, Lulu Qiao ... Ruhong Zhou
    Computer-Aided Aptamer Modeling and Optimization (CAAMO) enables structure-guided RNA aptamer affinity maturation, producing a SARS-CoV-2 RBD (receptor binding domain) binder that rivals neutralizing antibodies and retains predicted activity across variants.
    1. Developmental Biology
    2. Plant Biology

    Correction: Control of Arabidopsis shoot stem cell homeostasis by two antagonistic CLE peptide signalling pathways

    Jenia Schlegel, Gregoire Denay ... Rüdiger GW Simon
    1. Neuroscience

    The Crunchometer, a low-cost, open-source acoustic analysis of feeding microstructure

    Elvi Gil Lievana, Benjamin Arroyo ... Ranier Gutierrez
    Making the moment-to-moment dynamics of solid-food intake measurable in any laboratory enables researchers to map the brain circuits that control appetite and accelerate the development of treatments for obesity.
    1. Genetics and Genomics

    Fourfold lifespan extension in C. elegans daf-2 mutant males

    Mike Russell, Michelle Lin ... Liou Y Sun
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    ATP-driven conformational dynamics reveal hidden intermediates in a heterodimeric ABC transporter

    Matija Pečak, Christoph Nocker, Robert Tampé
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Computational and Systems Biology

    Benchmarking biochemical networks generated by large language models

    Jeevan Tewari, Benjamin W Dahl ... Jeffrey J Saucerman
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
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