Browse the latest research

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    1. Neuroscience

    Cerebellar climbing fibers impact experience-dependent plasticity in the mouse primary somatosensory cortex

    Abby Silbaugh, Kevin P Koster, Christian Hansel
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Neuroscience

    Microsaccades track shifting but not necessarily maintaining covert visual-spatial attention

    Anna M van Harmelen, Freek van Ede
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Developmental Biology

    Endothelial Slit2 guides the Robo1-positive sympathetic innervation during heart development

    Juanjuan Zhao, Susann Bruche ... Mathilda TM Mommersteeg
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology

    Hepatic Transthyretin knockdown alleviates NAFLD by enhancing SERCA2 function and inhibiting endoplasmic reticulum stress

    Yingzi He, Tian Yang ... Fenping Zheng
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Genetics and Genomics

    Stranded short nascent strand sequencing reveals the topology of DNA replication origins in Trypanosoma brucei

    Slavica Stanojcic, Bridlin Barckmann ... Yvon Sterkers
    Not revised
    Reviewed Preprint v1
    • Inadequate
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Timely vaccine strain selection and genomic surveillance improve evolutionary forecast accuracy of seasonal influenza A/H3N2

    John Huddleston, Trevor Bedford
    Reducing vaccine development time from 12 months to 6 reduces forecasting error by 25%, while reducing lags in genome sequence submission reduces uncertainty of current clade frequencies by 50%.
    1. Neuroscience

    Biophysical network modeling of temporal and stereotyped sequence propagation of neural activity in the premotor nucleus HVC

    Zeina Bou Diab, Marc Chammas, Arij Daou
    Songbird HVC sequences arise from a balance of ionic currents and structured inhibition, providing a mechanistic framework for understanding cortical sequence generation.
    1. Structural Biology and Molecular Biophysics

    Crossover in aromatic amino acid interaction strength between tyrosine and phenylalanine in biomolecular condensates

    David De Sancho, Xabier Lopez
    Hydration modulates aromatic interactions, explaining why Tyr is a stronger sticker than Phe in aqueous environments like protein condensates but not in the cores of folded proteins.
    1. Neuroscience
    2. Physics of Living Systems

    Sub-surface deformation of individual fingerprint ridges during tactile interactions

    Giulia Corniani, Zing S Lee ... Hannes P Saal
    Sub-surface imaging demonstrates that vertical shear beneath fingertip ridges enables high mechanical spatial resolution to support tactile sensing.