The complete synaptic connectome and the comprehensive annotation of all cell types based on a whole-body electron microscopy volume of an annelid larva.
Clinical, genetic, and model organism data collectively define PLCG1 as a disease-associated gene with diverse missense variants contributing to phenotypic heterogeneity.
The unbiased genetic screening and animal model experiments have characterized a new candidate pathogenic gene associated with high myopia, providing a potential therapeutic intervention target for controlling the disease.
Laura Dovek, Mahboubeh Ahmadi ... Vijayalakshmi Santhakumar
Evaluation of semilunar granule cell involvement in dentate gyrus contextual memory processing supports recruitment based on intrinsic and input characteristics while revealing limited contribution to ensemble refinement.
