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    1. Neuroscience

    Odors drive feeding through gustatory receptor neurons in Drosophila

    Hongping Wei, Thomas Ka Chung Lam, Hokto Kazama
    Odors directly activate taste neurons in Drosophila, revealing a peripheral mechanism of odor-taste integration that enhances feeding behavior.
    1. Cell Biology

    Efficiency and localisation of AURKA degradation by PROTACs is modulated by deubiquitinases UCHL5 and target-selective OTUD6A

    Annabel Cardno, Karen Roberts, Catherine Lindon
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Genetics and Genomics

    Chromosome-scale genome assembly of the European common cuttlefish Sepia officinalis

    Simone Rencken, Georgi Tushev ... Gilles Laurent
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Chromosomes and Gene Expression

    Srs2 binding to proliferating cell nuclear antigen (PCNA) and its sumoylation contribute to replication protein A (RPA) antagonism during the DNA damage response

    Jiayi Fan, Nalini Dhingra ... Xiaolan Zhao
    Srs2 binding to PCNA and subsequent Mec1-dependent sumoylation regulate RPA-mediated checkpoint signaling.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Trained immunity in the lung

    Elina Idiiatullina, Dane Parker
    Several studies have now demonstrated that trained immunity occurs in the airways to several pathogens and products, while its utility is yet to be determined.
    1. Neuroscience

    Interleukin-4 induces CD11c+ microglia leading to amelioration of neuropathic pain in mice

    Keita Kohno, Ryoji Shirasaka ... Makoto Tsuda
    Increasing CD11c+ microglial subsets in the spinal dorsal horn by intrathecal treatment of interleukin-4 alleviate pain hypersensitivity caused by nerve injury.
    1. Developmental Biology

    Meteorins regulate the formation of the left-right organizer and the establishment of vertebrate body asymmetry

    Fanny Eggeler, Jonathan Boulanger-Weill ... Filippo Del Bene
    Genetic analyses in zebrafish reveal a new role for the Meteorin protein family in the left-right asymmetry patterning during embryonic vertebrate development.
    1. Ecology

    Loss of olfaction reduces caterpillar performance and increases susceptibility to a natural enemy

    Qi Wang, Yufei Jia ... Alexander Haverkamp
    The sense of smell is crucial for insect larvae not only to find a suitable food source but also for finding safe spaces which are free of their natural enemies.
    1. Biochemistry and Chemical Biology

    Phage-displayed synthetic library and screening platform for nanobody discovery

    Baolong Xia, Ah-Ram Kim ... Norbert Perrimon
    A phage-displayed synthetic library and screening platform offer a streamlined, cost-effective solution for nanobody discovery.
    1. Neuroscience

    Separable dorsal raphe dopamine projections mimic the facets of a loneliness-like state

    Christopher R Lee, Gillian A Matthews ... Kay M Tye
    Optogenetic manipulations and neural circuit interrogation reveal that dorsal raphe dopamine circuits can emulate different facets of a loneliness-like state, including prosociality, aversion, and vigilance.