Abundant single-stranded telomeric DNA distinguishes alternative lengthening of telomeres-positive cells and represents a potential biomarker and therapeutic vulnerability.
Marie-Therese Fischer, Katherine S Xue ... Lauren A O'Connell
Direct skin contact during parental care in poison frogs transmits host-adapted microbes to tadpoles, where some bacterial taxa may persist on the skin through early development.
Elevated ubiquitin phosphorylation disrupts proteasomal function, creating a self-amplifying cycle that drives progressive protein aggregation and neuronal injury across multiple neurodegenerative conditions.
