Immunology and Inflammation

Latest articles

1. 1. Immunology and Inflammation
   2. Neuroscience

   Intravital calcium imaging of meningeal macrophages reveals niche-specific dynamics and aberrant responses to brain hyperexcitability

   Simone Carneiro-Nascimento, Chao Wei ... Dan Levy
2. 1. Immunology and Inflammation
   2. Cancer Biology

   The 1000+ mouse project: large–scale spatiotemporal parametrization and modeling of preclinical cancer immunotherapies

   Adam L Kenet, Sooraj Achar ... Grégoire Altan-Bonnet
3. 1. Immunology and Inflammation

   TGF-β drives the conversion of conventional NK cells into uterine tissue-resident NK cells to support murine pregnancy

   Josselyn D Barahona, Liping Yang ... Wayne M Yokoyama
4. 1. Medicine
   2. Immunology and Inflammation

   Endothelial TLR4 signaling drives tissue inflammation, Claudin-5 internalization, and vascular barrier breakdown in a mouse model of neonatal meningitis

   Philip V Seegren, Amir Rattner ... Jeremy Nathans
5. 1. Immunology and Inflammation

   Tolerance to Lung Infection in TWIK2 K⁺ Efflux Mediated Macrophage Trained Immunity

   Josh Thompson, Yufan Li ... Jingsong Xu
6. 1. Immunology and Inflammation

   An IL-21R hypomorph circumvents functional redundancy to define STAT1 signaling in germinal center responses

   Christoph Jandl, Joanna Warren ... Cecile King
7. 1. Immunology and Inflammation

   A single microRNA miR-195 rescues the arrested B cell development induced by EBF1 deficiency

   Yuji Miyatake, Takeshi Kamakura ... Ai Kotani

   Mir195 enables Ebf1-deficient hematopoietic progenitor cells to mature into B cells, suggesting some miRNA can substitute for transcription factors in differentiation.
8. 1. Immunology and Inflammation

   Ly6G⁺ granulocytes-derived IL-17 limits protective host responses and promotes tuberculosis pathogenesis

   Priya Sharma, Raman Deep Sharma ... Dhiraj Kumar

   The IL-17–Ly6G⁺ granulocyte axis is a key driver and correlate of tuberculosis pathology and represents a potential target for improving vaccine-induced protection and therapeutic outcomes.
9. 1. Genetics and Genomics
   2. Immunology and Inflammation

   Polymorphisms in intron 1 of HLA-DRA differentially associate with type 1 diabetes and celiac disease and implicate involvement of complement system genes C4A and C4B

   Ozkan Aydemir, Jeffrey A Bailey ... TEDDY Study Group

   HLA-DRA intronic haplotype associates with opposite effects on type 1 diabetes and celiac disease, refining genetic risk prediction and implicating complement genes C4A and C4B in divergent autoimmune pathways.
10. 1. Immunology and Inflammation

    Single-cell transcriptomics identifies altered neutrophil dynamics and accentuated T-cell cytotoxicity in tobacco-flavored e-cigarette-exposed mouse lungs

    Gagandeep Kaur, Thomas Lamb ... Irfan Rahman

    Profiling cell-specific immune responses reveals altered neutrophil function and enhanced T-cell mediated cell death following acute in vivo exposure to tobacco-flavored e-cigarette aerosol using single-cell technology.