Immunology and Inflammation

Latest articles

1. 1. Immunology and Inflammation

   During an inflammatory response, zebrafish tnfa and tnfb are expressed by different cell types and have distinct expression kinetics

   Kaylee SE van Dijk, Christina Begon-Pescia ... Maria Forlenza
2. 1. Cancer Biology
   2. Immunology and Inflammation

   The 1000⁺ mouse project for large-scale spatiotemporal parametrization and modeling of preclinical cancer immunotherapies

   Adam L Kenet, Sooraj Achar ... Grégoire Y Altan-Bonnet

   An automated bioluminescent image analysis framework, maRQup, parametrizes tumor dynamics and provides quantitative metrics, enabling large-scale evaluation and optimization of preclinical cancer immunotherapies.
3. 1. Immunology and Inflammation
   2. Structural Biology and Molecular Biophysics

   Adaptor protein supersaturation drives innate immune signaling and cell fate

   Alejandro Rodriguez Gama, Tayla Miller ... Randal Halfmann

   In-cell biophysical analyses identify a sequence-encoded energy storage function of innate immune adaptor proteins that allows cells to respond quickly and decisively to pathogenic signals.
4. 1. Immunology and Inflammation

   Ex vivo and in vivo CRISPR/Cas9 screenings identify the roles of protein N-glycosylation in regulating T-cell activation and functions

   Yu Hong, Xiaofang Si ... Yu Zhang

   Inactivation of beta 1,4-galactosyltransferase 1 leads to enhanced T-cell receptor activation and CD8⁺ T-cell function by affecting the galactosylation of T-cell receptor and CD8.
5. 1. Immunology and Inflammation

   A Germinal Center Checkpoint of AIRE in B Cells Limits Antibody Diversification

   Jordan Z Zhou, Bihui Huang ... Kang Chen
6. 1. Cell Biology
   2. Immunology and Inflammation

   Clathrin-independent endocytosis and retrograde transport in cancer cells tune immune synapse organization and CD8 T cell response

   Shiqiang Xu, Alix Buridant ... Henri-François Renard
7. 1. Developmental Biology
   2. Immunology and Inflammation

   HEB collaborates with TCR signaling to upregulate Id3 and enable γδT17 cell maturation in the fetal thymus

   Johanna S Selvaratnam, Juliana Dutra Barbosa da Rocha ... Michele K Anderson
8. 1. Immunology and Inflammation

   Temporal single-cell analysis reveals age-associated delay in immune resolution after respiratory viral infection

   Yue Wu, Chaofan Li ... Jie Sun
9. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Reprogramming of host energy metabolism mediated by the TNF-iNOS-HIF-1α axis plays a key role in host resistance to Plasmodium infection

   Kely C Matteucci, Nathalia PS Leite ... Ricardo T Gazzinelli
10. 1. Immunology and Inflammation
    2. Neuroscience

    Microglia: Replacing the immune system of the brain

    Julie Rebejac, Soyon Hong

    A new method enables engineered immune progenitor cells to replace microglia in mice and reveals how a genetic mutation can lead to inflammation in the brain.