Immunology and Inflammation

Immunology and Inflammation

eLife reviews research spanning allergy, immunity and immunoregulation, inflammation and T-cell receptor signalling. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Immunology and Inflammation

    Integrated single cell multiomic profiling and functional validation reveal distinct cellular routes to human plasma cell differentiation

    Colin A Fields, James F Read ... Deepta Bhattacharya
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Evolutionary Biology
    2. Immunology and Inflammation

    Separating selection from mutation in antibody language models

    Frederick A Matsen IV, Will Dumm ... Hugh K Haddox
    Factoring out nucleotide-level mutation biases from antibody language models dramatically improves prediction of functional mutation effects while reducing computational cost by orders of magnitude.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Correlates of protection against African swine fever virus identified by a systems immunology approach

    Kirill Lotonin, Francisco Brito ... Artur Summerfield
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Immunology and Inflammation

    Nociceptor neurons control pollution-mediated neutrophilic asthma

    Jo-Chiao Wang, Amelia Kulle ... Sebastien Talbot
    Air pollution activates macrophage-derived artemin, sensitizing TRPA1 nociceptors to drive neutrophilic asthma, revealing new therapeutic targets for refractory airway inflammation.
    1. Immunology and Inflammation

    Beta-Glucan Modulates Monocyte Plasticity and Differentiation Capacity to Mitigate DSS-Induced Colitis

    Yinyin Lv, Yanyun Fan ... Hongzhi Xu
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Immunology and Inflammation

    During an inflammatory response, zebrafish tnfa and tnfb are expressed by different cell types and have distinct expression kinetics

    Kaylee SE van Dijk, Christina Begon-Pescia ... Maria Forlenza
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cancer Biology
    2. Immunology and Inflammation

    The 1000+ mouse project for large-scale spatiotemporal parametrization and modeling of preclinical cancer immunotherapies

    Adam L Kenet, Sooraj Achar ... Grégoire Y Altan-Bonnet
    An automated bioluminescent image analysis framework, maRQup, parametrizes tumor dynamics and provides quantitative metrics, enabling large-scale evaluation and optimization of preclinical cancer immunotherapies.
    1. Immunology and Inflammation
    2. Structural Biology and Molecular Biophysics

    Adaptor protein supersaturation drives innate immune signaling and cell fate

    Alejandro Rodriguez Gama, Tayla Miller ... Randal Halfmann
    In-cell biophysical analyses identify a sequence-encoded energy storage function of innate immune adaptor proteins that allows cells to respond quickly and decisively to pathogenic signals.

Senior editors

  1. Wendy S Garrett
    Wendy S Garrett
    Harvard T.H. Chan School of Public Health, United States
  2. Diane M Harper
    University of Michigan, United States
  3. Tony Ng
    King's College London, United Kingdom
  4. See more editors