Immunology and Inflammation

Latest articles

1. 1. Medicine
   2. Immunology and Inflammation
   3. Microbiology and Infectious Disease

   

   Focus Issue: Trained Immunity

   Edited by Satyajit Rath et al.

   Our latest Focus Issue looks at what we’ve learnt over the past decade and what’s next for the field of trained immunity.
2. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Focus Issue: Evolving our understanding of trained immunity

   Eva Kaufmann, Yahya Sohrabi ... Jos WM van der Meer

   The articles in this focus issue discuss progress towards a more complete understanding of memory in the innate immune system, and efforts to exploit "trained immunity" for the development of new vaccines and therapeutics.
3. 1. Immunology and Inflammation

   Layers of immunity: Deconstructing the Drosophila effector response

   Faustine Ryckebusch, Yao Tian ... Bruno Lemaitre

   New tools make it possible to investigate the timing and importance of different immune effectors in defense against infection.
4. 1. Immunology and Inflammation

   B cell expression of the enzyme PexRAP, an intermediary in ether lipid biosynthesis, promotes antibody responses and germinal center size

   Sung Hoon Cho, Marissa A Jones ... Mark R Boothby
5. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Bacteriology: How Shigella tackles host defences

   Yizhou Huang, Teresa LM Thurston

   The pathogenic bacteria Shigella avoids detection inside hosts cells by degrading RNF213, the protein responsible for sensing the presence of intracellular pathogens.
6. 1. Biochemistry and Chemical Biology
   2. Immunology and Inflammation

   Structure-based Design of Chimeric Influenza Hemagglutinins to Elicit Cross-group Immunity

   Karla M Castro, Reyhaneh Ayardulabi ... Bruno E Correia
7. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   IFIT1 is rapidly evolving and exhibits disparate antiviral activities across 11 mammalian orders

   Matthew B McDougal, Ian N Boys ... John W Schoggins

   Evolutionary changes in RNA binding and antiviral activity result in diverse IFIT1 functions across mammals, even among closely related species.
8. 1. Immunology and Inflammation

   Resident memory macrophages and trained innate immunity at barrier tissues

   Alisha Kang, Michael D'Agostino ... Zhou Xing

   The increasing knowledge of barrier tissue-resident memory macrophages and trained innate immunity (TII) will help develop both nontarget-specific and target-specific TII-based vaccine strategies.
9. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Glycosylated IgG antibodies accelerated the recovery of haemorrhagic fever with renal syndrome patients

   Chuansong Quan, Lu Wang ... Haifeng Hou
10. 1. Immunology and Inflammation

    Lipopolysaccharide stimulates dynamic changes in B cell metabolism to promote proliferation

    Dana MS Cheung, Momchil Razsolkov ... J Simon C Arthur