Research Articles

Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.

Latest articles

    1. Neuroscience

    Rhythmic sampling and competition of target and distractor in a motion detection task

    Changhao Xiong, Nathan M Petro ... Mingzhou Ding
    Spatially and temporally overlapping target and distractor are both rhythmically sampled at ~1 Hz, and the phase relationship between target sampling and distractor sampling predicts behavior.
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Roles of the membrane-binding motif and the C-terminal domain of RNase E in localization and diffusion in E. coli

    Laura Troyer, Yu-Huan Wang ... Sangjin Kim
    Single-molecule imaging uncovers how distinct membrane-binding motifs and the intrinsically disordered C-terminal domain control RNase E’s membrane association and diffusion, linking structural divergence to RNA-processing dynamics in bacteria.
    1. Neuroscience

    Glaucoma-associated Optineurin mutations increase transcellular degradation of mitochondria in a vertebrate optic nerve

    Yaeram Jeong, Chung-ha O Davis ... Nicholas Marsh-Armstrong
    Increased transfer of axonal mitochondria to optic nerve astrocytes after expression of glaucoma-associated Optineurin variants suggest that increased transcellular degradation of axonal mitochondria may play a causative role in at least some forms of glaucoma.
    1. Neuroscience

    High cognitive violation of expectations is compromised in cerebellar ataxia

    Leonardo Daniel, Eli Vakil, William Saban
    Across three experiments, the cerebellum was found to support discrete sequential problems in higher cognition by processing expectation violations.
    1. Neuroscience

    Longitudinal awake imaging of mouse deep brain microvasculature with super-resolution ultrasound localization microscopy

    Yike Wang, Matthew R Lowerison ... Pengfei Song
    Ultrasound localization microscopy in awake mice enables high-resolution imaging of cerebral microvasculature in a natural physiological state, eliminates confounding effects of anesthetics, and supports reliable longitudinal vascular assessment across weeks.
    1. Evolutionary Biology

    Heterozygosity at a conserved candidate sex determination locus is associated with female development in the clonal raider ant (Ooceraea biroi)

    Kip D Lacy, Jina Lee ... Daniel JC Kronauer
    A complementary sex determination locus is conserved in ants and dates back to approximately 112 million years ago.
    1. Evolutionary Biology

    Convergent iridescence and divergent chemical signals in sympatric sister-species of Amazonian butterflies

    Joséphine Ledamoisel, Bruno Buatois ... Violaine Llaurens
    Ecological interactions exert contrasting evolutionary pressures on sympatric Morpho butterflies, promoting convergence in iridescence but divergence in chemical cues, illustrating how ecological interactions mediate trait evolution and sister-species coexistence.
    1. Neuroscience

    Mixed evidence for the rhythmicity of auditory perceptual judgements in humans

    Cécile Fabio, Christoph Kayser
    Across multiple experiments, the evidence for any rhythmicity of auditory perception remains difficult to establish.
    1. Developmental Biology

    Sox9 prevents retinal degeneration and is required for limbal stem cell differentiation in the adult mouse eye

    Alicia Hurtado, Victor López-Soriano ... Francisco Javier Barrionuevo
    The Sox9 gene is necessary for maintaining vision in the mouse adult eye, acting as an essential factor for retinal and corneal function.
    1. Immunology and Inflammation

    Layers of immunity: Deconstructing the Drosophila effector response

    Faustine Ryckebusch, Yao Tian ... Bruno Lemaitre
    New tools make it possible to investigate the timing and importance of different immune effectors in defense against infection.