Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Genetic information in cancer cells reveals the strength of cancer–immune interactions in an individual-based stochastic model, which captures explicit interactions between cancer and effector cells.
Models were more consistent than individual experts but performed comparably to ensembles of many experts and relative performance varied by month, justifying the use of combined model and expert forecast methodologies.
Diffusion-weighted magnetic resonance spectroscopy and microstructural modelling longitudinally tracks cell-specific cerebellar development to non-invasively monitor, and better understand, early brain microstructure.
Chronic stress impairs the autoinhibition in locus coeruleus neurons by inducing the internalization of α2A adrenaline receptors, which causes their overexcitation and consequently induces their degeneration by producing active asparagine endopeptidase.
A novel approach has been developed to partition the net biodiversity effect into components associated with positive, negative, and competitive species interactions.
Ana Teresa López-Jiménez, Dominik Brokatzky ... Serge Mostowy
High-content high-resolution microscopy coupled with deep learning-based analysis reveals novel phenotypes at the single-cell level during Shigella infection.
Megakaryocytes form a 3D cage of laminin and collagen IV that stabilizes them within their vascular niche, while β1/β3 integrins and MMP are key regulators that assist megakaryocyte maturation and intravasation.
Introducing premature visual experience by opening the closed eyelids early in ferrets caused many cells in the primary visual cortex to mature improperly.
