Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Yi-Ting Chang, Eric A Finkel ... Daniel H O'Connor
Preparatory states within the motor cortex play a critical role in selecting an appropriate action in response to sensory input, dependent on the context.
A combined theoretical and experimental study revealed the mechanistic and structural basis of mutational effects on allostery and provided insights into the intrinsic connection of intra- and inter-domain properties.
Ivan Castello-Serrano, Frederick A Heberle ... Ilya Levental
Direct measurements of trafficking kinetics between organelles of the secretory pathway suggest that lipid-driven membrane domains laterally sort proteins during membrane traffic.
Conditional abolishment of a G protein subunit in a subset of ectopic tuft cells engenders severer injury, slower recovery, and increased fatality following the infection of the influenza viruses.
Pascal Forcella, Niklas Ifflander ... Verdon Taylor
Extensive analysis shows that the RNA-binding protein SAFB binds to Drosha in hippocampal stem cells and controls oligodendrocyte fate commitment through post-transcriptional regulation of NFIB expression.
Giuseppina Porciello, Alessandro Monti ... Salvatore Maria Aglioti
Direct measures of inner gastrointestinal signals via ingestible capsules highlight the role of stomach pH in shaping human feelings of disgust, fear and happiness.
The first neurodevelopmental study using a novel, wearable brain imaging system based on optically pumped magnetometers, shows age-related changes in neural oscillatory task responses and cortical functional connectivity.