Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Cryo-electron microscopy and high-speed atomic force microscopy analyses of an epilepsy-related ligand–receptor complex LGI1–ADAM22 reveal the three-dimensional structure and dynamics of the 3:3 heterohexameric assembly of LGI1–ADAM22.
Although eIF2A is thought to be a translation initiation factor, loss of eIF2A has no effect on cellular mRNA translation in either unstressed or stressed conditions.
Extended multi-attribute attentional drift diffusion model reveals how attentional dynamics and weight shifts lead to less healthy decisions under hunger.
The jellyfish embryonic body axis is globally coordinated by conserved planar cell polarity (PCP) mechanisms and oriented by localised Wnt3 in two steps, highlighting PCP’s role in animal axis evolution.
SHAPE-MaP reveals functional RNA structures in the porcine epidemic diarrhea virus genome, enabling targeted siRNA design and offering a promising strategy to inhibit viral replication.
Active vision dynamically refines spatiotemporal neural representations, optimising visual processing through scanning behaviour and non-associative learning, providing insights into efficient sensory encoding in dynamic environments.
CD131 contributes to intestinal inflammation in ulcerative colitis, possibly by promoting the infiltration of macrophages, while targeting CD131 might potentially be a treatment remedy for ulcerative colitis.
