Figure 2—figure supplement 5. | TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells

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TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells

Figure 2—figure supplement 5.

Affiliation details

Cold Spring Harbor Laboratory, United States; Stony Brook University, United States; Huntington Hospital, Northwell Health, United States; University of Southern California, United States; Cancer Research UK – Cambridge Institute, University of Cambridge, United Kingdom
Figure 2—figure supplement 5.
Download figureOpen in new tabFigure 2—figure supplement 5. Knockdown efficiencies of the indicated siRNAs in A549 cells.

Knockdown efficiency upon transfection with the indicated siRNA oligonucleotides and compared to scramble siRNA-transfected control cells. Cells were collected 3 days post transfection and analyzed for expression of the indicated mRNA. Each bar represents mean ± SD of three replicates from two independent experiments and represents mRNA expression of the indicated gene normalized to GAPDH expression of each cell line. p-value *<0.05, **<0.005, paired t-test.

DOI: http://dx.doi.org/10.7554/eLife.21615.015