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    1. Immunology and Inflammation
    2. Stem Cells and Regenerative Medicine

    Stem cell infusion boosts sepsis survival in mice

    New findings highlight transfusions of bone-marrow stem cells as a potential treatment approach for sepsis patients.
    1. Cell Biology
    2. Medicine

    Study identifies potential new approach for treating diabetes complications

    Findings shed new light on how diabetes causes tissue damage when oxygen levels drop, and point to the repression of a protein complex as a possible treatment target.
    1. Ecology
    2. Microbiology and Infectious Disease

    Climate change and extreme weather will have complex effects on disease transmission

    Temperature variation affects pathogens and their hosts in distinct ways, and these organisms are influenced by the type of variation and the average background temperature it is applied to.
    1. Computational and Systems Biology

    Virtual patient ‘surrogates’ can personalise cancer treatments

    Mathematical models used as patient surrogates could help clinicians select the best cancer treatment before going to the patient’s bedside.
    1. Medicine

    Study identifies potential target for osteoporosis treatments

    By identifying a mechanism behind bone strengthening in response to stress, scientists may have found a promising new target for treating conditions that cause bone loss.
    1. Epidemiology and Global Health
    2. Medicine

    Protracted inflammation linked to post-COVID lung problems

    New findings suggest monitoring COVID-19 patients for signs of inflammation could help identify those at risk of long-term lung problems.
  1. Media coverage: December roundup of eLife papers in the news

    High-profile news coverage that eLife papers generated in December 2021, including CTV News, the Daily Mail and The Atlantic.
    1. Epidemiology and Global Health

    Urinary metabolic ‘signatures’ predict diet quality and metabolic health in European children

    New evidence supports public health efforts to recommend following a Mediterranean diet and limiting the consumption of processed foods in childhood.
    1. Computational and Systems Biology
    2. Medicine

    Combined 3D modelling technique predicts abnormal heart rhythms in patients with genetic heart disease

    A new, personalised heart modelling approach can predict abnormal heart rhythms and risk of sudden death in patients with hypertrophic cardiomyopathy, and may help determine who might benefit from a defibrillator.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Pre-existing immune cells can predict early response to hepatitis B vaccine

    Immunosequencing of T cells, combined with machine learning techniques, may enable scientists to predict which patients will have early, strong protection against hepatitis B infection following vaccination.