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Whole-genome sequencing of people who live beyond 105 and 110 years reveals unique genetic signatures linked to protective processes such as DNA repair.

Study identifies the mechanisms that cause muscle weakness experienced by people with Becker disease, providing options for possible new therapies.

A scan of health data on more than five million people for links between blood type and more than 1,000 diseases reveals new connections and supports previously reported ones.

Trans-kingdom imbalances in the gut microbes of newborns may increase the risk of asthma later in life, providing a possible target for treating the condition.

A comprehensive roadmap of muscle decline with age in mice reveals possible new targets for treatments, including the molecule Klotho.

Findings suggest combination gene therapies that target multiple causes of eye cell death in mice could be an effective approach for treating people with retinitis pigmentosa and similar conditions.

Comprehensive analyses provide new biological insights on the aging process in mice and will aid future studies on aging and related topics.

Genetically modifying mosquitoes to express antimalarial genes and pass them on to their offspring is being tested as a new strategy to eliminate malaria.

High-profile news coverage that eLife papers generated in March 2021, including The Guardian, The Telegraph and Science News.

Study suggests that high social status contributes to accelerated aging in baboons, despite its other advantages.