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A comprehensive roadmap of muscle decline with age in mice reveals possible new targets for treatments, including the molecule Klotho.

Findings suggest combination gene therapies that target multiple causes of eye cell death in mice could be an effective approach for treating people with retinitis pigmentosa and similar conditions.

Comprehensive analyses provide new biological insights on the aging process in mice and will aid future studies on aging and related topics.

Genetically modifying mosquitoes to express antimalarial genes and pass them on to their offspring is being tested as a new strategy to eliminate malaria.

High-profile news coverage that eLife papers generated in March 2021, including The Guardian, The Telegraph and Science News.

Study suggests that high social status contributes to accelerated aging in baboons, despite its other advantages.

A clinical study finds a biomarker for the action of glucocorticoids that could be used for developing tests to help clinicians tailor treatments.

Supplementation of the nutrient selenium protects against diet-induced obesity and may extend the lifespan of mice by controlling energy-regulating hormones.

The first known study to measure SARS-CoV-2 viral load in a variety of organs and tissues may aid our understanding of how COVID-19 develops following infection.

A flipped section of the Y chromosome may put men at risk of infertility, especially as they age – a finding that may help at-risk individuals take steps to preserve their fertility.