250 results found
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    A phylogenetic transform enhances analysis of compositional microbiota data

    Justin D Silverman, Alex D Washburne ... Lawrence A David
    The PhILR transform uses an evolutionary model to overcome statistical challenges associated with microbiota surveys.
    1. Microbiology and Infectious Disease

    PGFinder, a novel analysis pipeline for the consistent, reproducible, and high-resolution structural analysis of bacterial peptidoglycans

    Ankur V Patel, Robert D Turner ... Stéphane Mesnage
    PGFinder is an open-source software dedicated to the analysis of peptidoglycan mass spectrometry data that paves the way for peptidoglycomics.
    1. Evolutionary Biology

    Support for a clade of Placozoa and Cnidaria in genes with minimal compositional bias

    Christopher E Laumer, Harald Gruber-Vodicka ... Gonzalo Giribet
    Protein coding genes strongly support a sister group relationship between Placozoa and Cnidaria to the exclusion of Bilateria, contradicting previous phylogenies, which have likely been misled by pervasive compositional heterogeneity.
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    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Consistent and correctable bias in metagenomic sequencing experiments

    Michael R McLaren, Amy D Willis, Benjamin J Callahan
    A mathematical model of bias in marker-gene and metagenomic sequencing measurements explains systematic errors in defined mixtures of microbial species, and enables quantitative and reproducible investigation of biological communities.
    1. Ecology
    2. Microbiology and Infectious Disease

    Relationships between community composition, productivity and invasion resistance in semi-natural bacterial microcosms

    Matt Lloyd Jones, Damian William Rivett ... Thomas Bell
    Resident members of natural bacterial communities limit the growth of non-resident bacteria primarily by increasing overall community growth.
    1. Neuroscience

    A compositional neural code in high-level visual cortex can explain jumbled word reading

    Aakash Agrawal, KVS Hari, SP Arun
    Viewing a jumbled word activates an efficient visual representation in high-level visual cortex that is matched to stored words in the word form area.
    1. Neuroscience

    Neural assemblies uncovered by generative modeling explain whole-brain activity statistics and reflect structural connectivity

    Thijs L van der Plas, Jérôme Tubiana ... Georges Debrégeas
    A data-driven network model offers an interpretable and physiologically sound description of the whole-brain spontaneous neural activity of zebrafish larvae.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    An updated phylogeny of the Alphaproteobacteria reveals that the parasitic Rickettsiales and Holosporales have independent origins

    Sergio A Muñoz-Gómez, Sebastian Hess ... Andrew J Roger
    Diverse sophisticated phylogenetic analyses update the phylogeny of the Alphaproteobacteria and show that the parasitic Holosporales is a derived group within the Rhodospirillales order which comprises primarily free-living alphaproteobacteria.
    1. Ecology
    2. Evolutionary Biology

    Phylogenomic and mitogenomic data can accelerate inventorying of tropical beetles during the current biodiversity crisis

    Michal Motyka, Dominik Kusy ... Ladislav Bocak
    Integrated phylogenomics and mitochondrial DNA inventory of net-winged beetles across three continents suggest ~1000 undescribed species, biodiversity hot spots, and phylogeny-based classification that sets up the basis for further research.
    1. Ecology
    2. Microbiology and Infectious Disease

    Universal gut microbial relationships in the gut microbiome of wild baboons

    Kimberly E Roche, Johannes R Bjork ... Elizabeth A Archie
    In baboon gut microbiota, most pairwise correlations in bacterial abundances are weak and negative, and bacterial correlation patterns are largely shared across hosts, rather than personalized to each hosts.

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