14,740 results found
    1. Genetics and Genomics
    2. Neuroscience

    The ion channel ppk301 controls freshwater egg-laying in the mosquito Aedes aegypti

    Benjamin J Matthews, Meg A Younger, Leslie B Vosshall
    The ion channel ppk301 is required for the evaluation of water purity during egg-laying, which promotes offspring survival in the arboviral vector mosquito Aedes aegypti.
    1. Microbiology and Infectious Disease

    The kinetoplastid-infecting Bodo saltans virus (BsV), a window into the most abundant giant viruses in the sea

    Christoph M Deeg, Cheryl-Emiliane T Chow, Curtis A Suttle
    Bodo saltans virus defines the most abundant giant viruses in the ocean and highlights the genomic plasticity, rooted in evolutionary arms races, that gave rise to giant viruses.
    1. Neuroscience

    Monkey EEG links neuronal color and motion information across species and scales

    Florian Sandhaeger, Constantin von Nicolai ... Markus Siegel
    Using Monkey EEG as a bridge technology, color and motion representations in human MEG are linked to microcircuit activity in ventral stream areas.
    1. Neuroscience
    2. Physics of Living Systems

    Imaging of brain electric field networks with spatially resolved EEG

    Lawrence R Frank, Vitaly L Galinsky ... Antigona Martinez
    A physics-based solution to the electroencephalography (EEG) inverse problem enables whole-brain electric field imaging with high spatial and temporal resolution using standard EEG systems.
    1. Neuroscience

    Single synapse evaluation of the postsynaptic NMDA receptors targeted by evoked and spontaneous neurotransmission

    Austin L Reese, Ege T Kavalali
    In a population of mammalian central synapses, spontaneous and evoked neurotransmitter release processes are independently distributed; yet, postsynaptic receptors within a single synapse preferentially receive neurotransmitter from only one mode of release.
    1. Neuroscience

    Human Neocortical Neurosolver (HNN), a new software tool for interpreting the cellular and network origin of human MEG/EEG data

    Samuel A Neymotin, Dylan S Daniels ... Stephanie R Jones
    Human Neocortical Neurosolver is a new user-friendly software tool for researchers to develop and test hypotheses on cellular/circuit origins of human MEG/EEG signals using a biophysical model.
    1. Neuroscience

    Optical detection of three modes of endocytosis at hippocampal synapses

    Natali L Chanaday, Ege T Kavalali
    Single synaptic vesicle imaging shows that kinetically distinct endocytic pathways are differentially regulated by calcium and temperature, and influence the fidelity of synaptic vesicle protein retrieval.
    1. Neuroscience

    Bayesian analysis of phase data in EEG and MEG

    Sydney Dimmock, Cian O'Donnell, Conor Houghton
    A Bayesian model of phase angles illustrates a novel approach to the analysis of phase coherence in frequency-tagged experiments.
    1. Cancer Biology
    2. Cell Biology

    ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor

    Zineb Mounir, Joshua M Korn ... Raymond A Pagliarini
    The transcription factor ERG recruits the PRMT5 enzyme to methylate the androgen receptor, presenting a post-translational regulatory mechanism that could be therapeutically exploited to control cell proliferation.
    1. Developmental Biology

    MMP14 cleaves PTH1R in the chondrocyte-derived osteoblast lineage, curbing signaling intensity for proper bone anabolism

    Tsz Long Chu, Peikai Chen ... Kathryn Song Eng Cheah
    MMP14 activity-mediated cleavage of the ectodomain of PTH1R modulates PTH signaling in the chondrocyte-derived osteoblast lineage, regulating osteogenesis and thereby bone metabolism, with therapeutic significance for bone-wasting diseases.

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