The ion channel ppk301 is required for the evaluation of water purity during egg-laying, which promotes offspring survival in the arboviral vector mosquito Aedes aegypti.

Bodo saltans virus defines the most abundant giant viruses in the ocean and highlights the genomic plasticity, rooted in evolutionary arms races, that gave rise to giant viruses.

Using Monkey EEG as a bridge technology, color and motion representations in human MEG are linked to microcircuit activity in ventral stream areas.

In a population of mammalian central synapses, spontaneous and evoked neurotransmitter release processes are independently distributed; yet, postsynaptic receptors within a single synapse preferentially receive neurotransmitter from only one mode of release.

Human Neocortical Neurosolver is a new user-friendly software tool for researchers to develop and test hypotheses on cellular/circuit origins of human MEG/EEG signals using a biophysical model.

Single synaptic vesicle imaging shows that kinetically distinct endocytic pathways are differentially regulated by calcium and temperature, and influence the fidelity of synaptic vesicle protein retrieval.

A Bayesian model of phase angles illustrates a novel approach to the analysis of phase coherence in frequency-tagged experiments.

The transcription factor ERG recruits the PRMT5 enzyme to methylate the androgen receptor, presenting a post-translational regulatory mechanism that could be therapeutically exploited to control cell proliferation.

MMP14 activity-mediated cleavage of the ectodomain of PTH1R modulates PTH signaling in the chondrocyte-derived osteoblast lineage, regulating osteogenesis and thereby bone metabolism, with therapeutic significance for bone-wasting diseases.

Spontaneous fusion of vesicles at synapses is regulated independently of fusion triggered by action potentials, adding to evidence that the two types of fusion have distinct functions.