111 results found
    1. Evolutionary Biology

    Improved use of a public good selects for the evolution of undifferentiated multicellularity

    John H Koschwanez, Kevin R Foster, Andrew W Murray
    The ability to share resources for the benefit of all members of a group may have driven ancient organisms to evolve from a unicellular to a multicellular state.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Evolution of multicellularity by collective integration of spatial information

    Enrico Sandro Colizzi, Renske MA Vroomans, Roeland MH Merks
    Selection for undifferentiated multicellularity emerges in an evolutionary cell-based model because a collective of cells performs chemotaxis better than single cells in a noisy environment.
    1. Evolutionary Biology

    Cave Bacteria: Illuminating a new path to multicellularity

    Sayantan Datta, William C Ratcliff
    A new species of multicellular bacteria broadens our understanding of prokaryotic multicellularity and provides insight into how multicellular organisms arise.
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    1. Evolutionary Biology

    Regulated aggregative multicellularity in a close unicellular relative of metazoa

    Arnau Sebé-Pedrós, Manuel Irimia ... Iñaki Ruiz-Trillo
    The transition to the aggregative stage of Capsaspora owczarzaki, a close unicellular relative to Metazoa, is associated with significant upregulation of orthologs of genes that are important for multicellularity in metazoans.
    1. Cell Biology
    2. Evolutionary Biology

    Evolution of an ancient protein function involved in organized multicellularity in animals

    Douglas P Anderson, Dustin S Whitney ... Kenneth E Prehoda
    Experimentally reconstructing the evolution of the molecular complex that animals use to orient the mitotic spindle establishes a simple genetic and physical mechanism for the emergence of a function essential for multicellularity.
    1. Developmental Biology
    2. Evolutionary Biology

    Gene age shapes the transcriptional landscape of sexual morphogenesis in mushroom-forming fungi (Agaricomycetes)

    Zsolt Merényi, Máté Virágh ... László G Nagy
    Allele-specific expression, natural antisense transcripts, and developmental gene expression, but not RNA editing or developmental hourglass, act in concert to shape the transcriptome during the fruiting body formation of complex multicellular fungi.
    1. Microbiology and Infectious Disease

    A serine sensor for multicellularity in a bacterium

    Arvind R Subramaniam, Aaron DeLoughery ... Yunrong Chai
    Biofilm formation by Bacillus subtilis relies on a sensing mechanism for the amino acid serine that does not depend on a dedicated protein or RNA.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Genomic innovation of ATD alleviates mistranslation associated with multicellularity in Animalia

    Santosh Kumar Kuncha, Vinitha Lakshmi Venkadasamy ... Rajan Sankaranarayanan
    Identification of a two-tier functional redundancy to combat proteostasis imbalance induced due to tRNA expansion and oxidative stress in multicellular animals.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Highly regulated, diversifying NTP-dependent biological conflict systems with implications for the emergence of multicellularity

    Gurmeet Kaur, A Maxwell Burroughs ... L Aravind
    Multicellular and socially aggregating prokaryotes contain previously undescribed, chaperone-based systems predicted to mediate defensive biological conflicts, several components of which are thematically similar antecedents of eukaryotic apoptosis pathways.
    1. Evolutionary Biology

    Novel multicellular prokaryote discovered next to an underground stream

    Kouhei Mizuno, Mais Maree ... Kazuya Morikawa
    A new bacterium isolated from an underground stream shows a novel multicellularity by self-organizing its filamentous cells like a liquid crystal and accommodating daughter cells in a sequential manner, which would be a new extant model of prokaryotic multicellularity.

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