A temperate bacteriophage reprograms the oxygen response of a bacterial signaling system by replacing a host-encoded promoter with a phage-encoded promoter.

An in-depth map of ATR signaling during mouse meiosis is revealed using a combination of genetic and pharmacological approaches coupled to quantitative mass spectrometry.

From public microbial genomes, VirSorter revealed 12,498 viral genome sequences that expand the map of the global virosphere and whose analyses improve understanding of viral taxonomy, evolution and virus-host interactions.

Isolation of a gokushovirus capable of lysogenizing enterobacteria challenges previous notions about the biology of the most prolific phages within the Microviridae and facilitates experimental study in a model organism.

Mutualistic viruses called virophages are common genome inhabitants of a marine protist, where they may protect host populations from giant viruses.

An endosymbiont transgene in Drosophila melanogaster exhibits remarkable phenotypic sensitivity, including to synonymous codon changes.

The dominant MRSA circulating in European livestock has stably maintained genes associated with resistance to antibiotic treatments over several decades and when it is transmitted to humans it can rapidly acquire genes that allow it to evade human immune responses.

The switch from mitotic cell cycles to the one meiotic cell cycle in each generation is triggered through dramatic upregulation of a broad gene expression program by transcriptional regulator STRA8.

A Topbp1 mutant mouse reveals a non-canonical role for the ATR-TOPBP1 signaling axis in meiosis, separating ATR signaling and meiotic sex chromosome inactivation from sex body formation.

A compendium of critical genomic numbers for viruses through the lenses of different viral classification systems.