Alfredo Sánchez-Tójar, Shinichi Nakagawa ... Julia Schroeder
Meta-analysis takes down a textbook example in behavioural and evolutionary ecology, and demonstrates the existence of biases in the current scientific publishing culture.
Peter-Paul Zwetsloot, Mira Van Der Naald ... Kimberley E Wever
Funnel plots of the Standardized Mean Difference versus the standard error are prone to distortion, leading to false-positive tests for funnel plot asymmetry, and therefore using the Normalised Mean Difference, or a sample size-based precision estimate, are more reliable alternatives.
Silas Boye Nissen, Tali Magidson ... Carl T Bergstrom
Publication bias, in which positive results are preferentially reported by authors and published by journals, can restrict the visibility of evidence against false claims and allow such claims to be canonized inappropriately as facts.
An analysis of papers in which two or more authors shared first-author position found that male authors were more likely than female authors to appear first in the author list.
Alexis DJ Makin, John Tyson-Carr ... Marco Bertamini
A complete public catalogue of brain recording data from a single laboratory has revealed new scientific findings, and has also shed light on aspects of the scientific process, such as statistical power and publication bias.
Harriet Hunter, Dana de Gracia Hahn ... Jake P Mann
Animal studies of fatty liver disease over-estimate the benefit of drugs due to publication bias and are confounded by off-target weight loss, illustrating the challenge of successful translational across species.
Generative artificial intelligence, such as OpenAI’s ChatGPT, can be used to analyze scientific texts with specialized constructions, including peer review reports.
Valerie C Henderson, Nadine Demko ... Jonathan Kimmelman
Preclinical efficacy experiments testing sunitinib in animal cancer models display a lack of methodological rigour, with trim-and-fill analysis suggesting prominent publication bias that leads to an overestimation of treatment effect.
New open-source method contains all the tools for extracting open chromatin or RNA from thousands of single cells in parallel for <5% of the cost of state-of-the-art commercial alternatives, paving the way for whole-tissue atlasing and new protocol development.
Manoj M Lalu, Katrina J Sullivan ... Lauralyn McIntyre
A rigorous and transparent evaluation of mesenchymal stem cell therapy for sepsis suggests it may be efficacious, although the strength of these findings is tempered by threats to validity in the studies that were included.