10,156 results found
    1. Computational and Systems Biology
    2. Epidemiology and Global Health

    Characterizing human mobility patterns in rural settings of sub-Saharan Africa

    Hannah R Meredith, John R Giles ... Amy Wesolowski
    Mobile phone data reveal aspects of human mobility patterns in Sub-Saharan Africa missed by standard spatial models however, model estimates can be improved by accounting for trip urbanicity and region.
    1. Neuroscience

    Influence of sensory modality and control dynamics on human path integration

    Akis Stavropoulos, Kaushik J Lakshminarasimhan ... Dora E Angelaki
    Human path integration accuracy is strongly influenced by the underlying control dynamics, but less so when visual, rather than vestibular, feedback is available.
    1. Epidemiology and Global Health

    Using parasite genetic and human mobility data to infer local and cross-border malaria connectivity in Southern Africa

    Sofonias Tessema, Amy Wesolowski ... Bryan Greenhouse
    Combining parasite genetic and human mobility data can provide detailed information on local and cross-border connectivity, allowing programs to strengthen local and regional coordination for successful elimination of malaria.
    1. Epidemiology and Global Health

    Mapping imported malaria in Bangladesh using parasite genetic and human mobility data

    Hsiao-Han Chang, Amy Wesolowski ... Caroline Buckee
    Human mobility drives malaria importation within countries and threatens elimination interventions, but can be measured using new approaches that combine parasite genetics, mobile phone data, travel surveys and models.
    1. Epidemiology and Global Health

    Disentangling the rhythms of human activity in the built environment for airborne transmission risk: An analysis of large-scale mobility data

    Zachary Susswein, Eva C Rest, Shweta Bansal
    Fine-grain mobility data empirically quantify the propensity for human mixing to be indoors across the US and improve understanding of the relationship between the physical environment and infection risk in light of global change.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Stable population structure in Europe since the Iron Age, despite high mobility

    Margaret L Antonio, Clemens L Weiß ... Jonathan K Pritchard
    Reconstructing human mobility patterns using historical period genomes illustrates how the Roman Empire’s military and economic activities catalyzed an era of transient movement against the backdrop of generations-long prehistoric migrations.
    1. Neuroscience

    Modality-specific tracking of attention and sensory statistics in the human electrophysiological spectral exponent

    Leonhard Waschke, Thomas Donoghue ... Jonas Obleser
    Waschke and colleagues demonstrate that aperiodic EEG activity not only captures subtle attention-related changes in brain signals but also tracks 1/f-like sensory input.
    1. Immunology and Inflammation
    2. Neuroscience

    TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia

    Amit Jairaman, Amanda McQuade ... Michael D Cahalan
    Deletion of Alzheimer’s disease risk gene TREM2 augments sensitivity to the purinergic agonist ADP, leading to increased Ca2+ influx and reduced directional migration in human induced pluripotent stem cell-derived microglia.
    1. Cell Biology

    Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility

    Wondwossen M Yeshaw, Marianne van der Zwaag ... Ody CM Sibon
    VPS13A is associated with the endoplasmic reticulum, mitochondria and lipid droplets and is required for cellular processes that require interaction between these organells.
    1. Cell Biology

    The human cytoplasmic dynein interactome reveals novel activators of motility

    William B Redwine, Morgan E DeSantis ... Samara L Reck-Peterson
    Using a proximity-dependent labeling approach in living cells, the human cytoplasmic dynein-1 interactome was identified and a new family of dynein activators, ninein and ninein-like, was discovered.

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