7,528 results found
  1. Point of View: The NIH must reduce disparities in funding to maximize its return on investments from taxpayers

    Wayne P Wahls
    A more balanced distribution of NIH grant funding among investigators would strengthen the diversity of the research enterprise, increase the likelihood of scientific breakthroughs, and lead to a greater return on taxpayers' investments.
    1. Computational and Systems Biology

    Step-to-step variations in human running reveal how humans run without falling

    Nidhi Seethapathi, Manoj Srinivasan
    Natural step-to-step variations show how human running is stabilized, underscoring the importance of center of mass control and showing how humans run without falling despite muscle noise and uneven terrain.
    1. Computational and Systems Biology
    2. Chromosomes and Gene Expression

    Stochastic tuning of gene expression enables cellular adaptation in the absence of pre-existing regulatory circuitry

    Peter L Freddolino et al.
    Stochastic tuning of gene expression could be a common mechanism through which eukaryotic cells adapt to challenging external environments, potentially including survival of infectious organisms within the host and adaptation of cancer cells to chemotherapy.
    1. Developmental Biology
    2. Neuroscience

    Learning steers the ontogeny of an efficient hunting sequence in zebrafish larvae

    Konstantinos Lagogiannis et al.
    Early hunting experience modifies the kinematics of hunting in larval zebrafish to increase the probability of successfully capturing live prey.
    1. Evolutionary Biology
    Neighboring communities of bonobos hunt different prey species

    Social Learning: Does culture shape hunting behavior in bonobos?

    Andrew Whiten
    New evidence that neighboring communities of bonobos hunt different prey species, despite extensive overlaps in where they live and hunt, is difficult to explain without invoking cultural factors.
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    1. Neuroscience

    Low-frequency neural activity reflects rule-based chunking during speech listening

    Peiqing Jin et al.
    Neuroimaging reveals that the brain response to spoken language can be better explained by rule-based models than statistical models recently developed in artificial intelligence research.
    1. Neuroscience

    Pretectal neurons control hunting behaviour

    Paride Antinucci et al.
    A discrete population of genetically accessible pretectal neurons controls visually guided hunting behaviour in larval zebrafish.
    1. Neuroscience

    Feedforward motor information enhances somatosensory responses and sharpens angular tuning of rat S1 barrel cortex neurons

    Mohamed Khateb et al.
    Primary motor cortex afferents supra-linearly amplify the responses and sharpen angular tuning of neurons in the S1 barrel cortex.
    1. Neuroscience
    2. Physics of Living Systems

    Tuning of feedforward control enables stable muscle force-length dynamics after loss of autogenic proprioceptive feedback

    Joanne C Gordon et al.
    Running guinea fowl maintain stable running after loss of the stretch reflex in a major ankle extensor muscle, by increasing feedforward muscle activation to maintain ankle stiffness and work output.
    1. Biochemistry and Chemical Biology
    2. Immunology and Inflammation

    Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells

    Ben F Brian IV et al.
    The ubiquitin ligase c-Cbl preferentially targets unique-region phosphorylated LynA for rapid degradation, regulating its expression and differentially tuning signaling responsiveness in macrophages and mast cells.

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