35 results found
    1. Plant Biology

    The kinase LYK5 is a major chitin receptor in Arabidopsis and forms a chitin-induced complex with related kinase CERK1

    Yangrong Cao, Yan Liang ... Gary Stacey
    The chitin-triggered immune response is mediated by a LYK5 and CERK1 receptor complex in Arabidopsis.
    1. Plant Biology

    Anion channel SLAH3 is a regulatory target of chitin receptor-associated kinase PBL27 in microbial stomatal closure

    Yi Liu, Tobias Maierhofer ... Silke Robatzek
    S-type anion channel activity, which promotes stomatal closure and improves anti-fungal immunity in plants, is directly regulated through phosphorylation by a kinase of the chitin receptor complex.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Two complement receptor one alleles have opposing associations with cerebral malaria and interact with α+thalassaemia

    D Herbert Opi, Olivia Swann ... J Alexandra Rowe
    Analysis of a large Kenyan dataset may resolve previously conflicting studies by identifying polymorphisms which interact to modify the risk of cerebral malaria.
    1. Plant Biology

    Epidermal LysM receptor ensures robust symbiotic signalling in Lotus japonicus

    Eiichi Murakami, Jeryl Cheng ... Simona Radutoiu
    Functional analyses provide evidence for a complex Nod factor signalling where NFRe is necessary for maintaining an optimal symbiotic signalling in the susceptible root zone, and initiation of nodule primordia on the expanding root system.
    1. Microbiology and Infectious Disease

    Small RNAs from mitochondrial genome recombination sites are incorporated into T. gondii mitoribosomes

    Sabrina Tetzlaff, Arne Hillebrand ... Christian Schmitz-Linneweber
    Sequences at mitochondrial genome recombination sites are dually used as mRNAs and as rRNAs in actively translating mitoribosomes of T. gondii.
    1. Evolutionary Biology

    The essential role of Dnmt1 in gametogenesis in the large milkweed bug Oncopeltus fasciatus

    Joshua T Washington, Katelyn R Cavender ... Patricia J Moore
    The maintenance DNA methyltransferase DNMT1 is required for the transition of spermatogonia to spermatocytes both during larval testis development and adult sperm replenishment in the insect Oncopeltus fasciatus.
    1. Plant Biology

    The Rhizobial effector NopT targets Nod factor receptors to regulate symbiosis in Lotus japonicus

    Hanbin Bao, Yanan Wang ... Yangrong Cao
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Solid
    1. Neuroscience

    The activity-dependent histone variant H2BE modulates the life span of olfactory neurons

    Stephen W Santoro, Catherine Dulac
    A genome-organizing protein that is present only in the olfactory system of mice has been found to orchestrate changes in the relative numbers of different odor-sensing neurons on the basis of how active these neurons are.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Transcriptional profiling of Hutchinson-Gilford Progeria syndrome fibroblasts reveals deficits in mesenchymal stem cell commitment to differentiation related to early events in endochondral ossification

    Rebeca San Martin, Priyojit Das ... Rachel Patton McCord
    Age-stratified comparisons of gene expression in progeria patient fibroblasts reveals disruption of mesenchymal lineage pathways and points to a deficit in chondrogenic commitment in early development and a depletion of the mesenchymal lineage stem cell pool.
    1. Computational and Systems Biology

    Lack of evidence for increased transcriptional noise in aged tissues

    Olga Ibañez-Solé, Alex M Ascensión ... Ander Izeta
    An increase in transcriptional noise generally assumed to characterize aged cells and tissues is shown to derive instead from technical and biological issues that underlie single-cell RNA sequencing experiments.

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