A new study reveals structural details of the bacterial essential interactome, opening new avenues for antibiotic discovery.

The transcription factor Lola is defined as a non-canonical Hippo signaling component essential for Drosophila midgut homeostasis via its interaction with Warts and suppression on Dref and SkpA expression levels.

Experimental Piper gardens across five neotropical sites reveal complex contingencies in the influence of species and population-level biodiversity on the flow of resources to insect herbivores and ecosystem resilience to changes in water availability.

A new genetically encoded sensor robustly detects exogenously applied PAC1R ligands in vitro, ex vivo, and in vivo (in zebrafishes and mice) serving as a useful resource for probing PAC1R functions.

The transcription factor GATA6 selects the embryonic vessels that will be reorganized into the major thoracic arteries by promoting local differentiation of vascular smooth muscle cells.

Localized feedback on Fa4-Ds1 boundary complexes underlies polarized distribution of Fat4 and Ds1 and gives rise to planar cell polarity.

The transcription factor NFIL3 is essential for the development of a committed bone marrow precursor that gives rise to all known innate lymphoid cell lineages in mice.

Changes in cortical neural ensembles and heightened coupling between the hippocampus and cortex enable the eventual behavioral integration of memories with overlapping sequential information.

Serum amyloid A proteins bind retinol with nanomolar affinity, and do so by forming oligomers that create a hydrophobic pocket that shields retinol from the aqueous environment.

Gut macrophages produce complement component C1q, which modulates neurogenic activity of gut peristalsis and is thus a key regulator of gastrointestinal motility.