14 results found
    1. Developmental Biology
    2. Genetics and Genomics

    Augmentation of progestin signaling rescues testis organization and spermatogenesis in zebrafish with the depletion of androgen signaling

    Gang Zhai, Tingting Shu ... Zhan Yin
    Augmentation of progestin signaling promotes testis development and spermatogenesis independent from andorgen signaling in zebrafish.
    1. Cancer Biology
    2. Cell Biology

    Chromatin topology defines estradiol-primed progesterone receptor and PAX2 binding in endometrial cancer cells

    Alejandro La Greca, Nicolás Bellora ... Patricia Saragüeta
    Binding of progesterone receptor and transcription factor PAX2 to pre-assembled permissive chromatin compartments regulates endometrial cancer gene expression under estrogenic conditions.
    1. Neuroscience
    2. Epidemiology and Global Health

    Menopausal hormone therapy and the female brain: leveraging neuroimaging and prescription registry data from the UK Biobank cohort

    Claudia Barth, Liisa AM Galea ... Ann-Marie G de Lange
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Medicine

    Clearance of senescent decidual cells by uterine natural killer cells in cycling human endometrium

    Paul J Brighton, Yojiro Maruyama ... Jan Joris Brosens
    While acute senescence of decidualizing cells drives the inflammatory response underpinning uterine receptivity, subsequent clearance by activated natural killer cells transiently rejuvenates the cycling endometrium, enabling transition into a gestational tissue upon embryo implantation.
    1. Cell Biology

    Sex steroids regulate skin pigmentation through nonclassical membrane-bound receptors

    Christopher A Natale, Elizabeth K Duperret ... Todd W Ridky
    Two receptors have been identified that can be targeted in melanocytes with selective small molecule agonists to modulate human skin color.
    1. Cell Biology

    Modelling the impact of decidual senescence on embryo implantation in human endometrial assembloids

    Thomas M Rawlings, Komal Makwana ... Emma S Lucas
    The study of embryo-endometrial interactions in assembloid co-cultures identifies novel mechanisms of reproductive failure.
    1. Cell Biology

    Progesterone induces meiosis through two obligate co-receptors with PLA2 activity

    Nancy Nader, Lama Assaf ... Khaled Machaca
    Progesterone mediates nongenomic signaling in Xenopus oocyte meiosis by activating a PLA2 activity that requires two membrane receptors ABDH2 and mPRß.
    1. Evolutionary Biology

    Evolutionary transcriptomics implicates new genes and pathways in human pregnancy and adverse pregnancy outcomes

    Katelyn Mika, Mirna Marinić ... Vincent J Lynch
    Comparative studies of gene expression in the uterus during pregnancy identifies new genes important for pregnancy and associated with complications such as preterm birth.
    1. Cell Biology

    Hormone replacement therapy for postmenopausal atherosclerosis is offset by late age iron deposition

    Tianze Xu, Jing Cai ... Kuanyu Li
    Post-menopausal women with atherosclerosis need to take the correct timing for hormone replacement therapy.
    1. Neuroscience

    Neuropeptide B mediates female sexual receptivity in medaka fish, acting in a female-specific but reversible manner

    Towako Hiraki-Kajiyama, Junpei Yamashita ... Kataaki Okubo
    In the brain of medaka fish, neuropeptide B acts directly downstream of estrogen in a female-specific but reversible manner to mediate female receptivity to male courtship.

Refine your results by:

Type
Research categories