Single-cell transcriptomics combined with genetic analyses identify post-embryonic neural crest subpopulations and thyroid hormone dependencies in zebrafish adult pigment pattern development.

A technology allows rapid screening of vast numbers of transcriptional factor combinatorials on stem cell programming.

A chemical screen reveals that a compound used to treat a parasitic disease can trigger pluripotent stem cells to become neurons, uncovering a novel mechanism behind neuronal development.

Genetic and physiological analyses demonstrate the essential role of the transcription factor HIF-2alpha in the sympathetic nervous system control of the ventilatory response to hypoxia.

Single-cell transcriptome analysis of sacral compared with vagal neural crest-derived cells in the developing chick enteric nervous system reveals both similarities and differences between these two cell populations.

Production of remyelinating subventricular zone oligodendrocyte progenitors is stimulated by transient abrogation of thyroid hormone signalling in the adult neural stem cell niche.

Chronic inhibition of mTORC1 signaling strongly affects the morphology, physiology and output of dopamine neurons leading to impaired dopaminergic function in mice.

Irreversible differentiation into somatic cells is evolutionarily optimal if changing cell phenotype is costly, a few somatic cells already improve the organism's performance, and the organism is large enough.

Cells of the xanthophore lineage form projections that allow them to communicate with other pigment cells during adult pigment pattern formation in zebrafish, but not in the closely-related pearl danio.

Mucosal-associated invariant T cells, an emerging member of the innate-like T cells abundant in humans bridging the innate and the adaptive immunity, could be exploited as a novel tool for cancer immunotherapy through cell reprogramming.